OMIX008711

1Summary
Title TCL1A in naive B cells as a therapeutic target for type 1 diabetes
Description In this study, we collected peripheral blood mononuclear cells from patients newly diagnosed with T1D and the patients' parents for single-cell RNA sequencing, and performed bulk RNA seq on Ramos cells treated with the AKT2 inhibitor CCT128930 to further investigate the disease pathogenesis of T1D.
Organism Homo sapiens
Data Type Expression Profiling
Data Accessibility Controlled-access
BioProject PRJCA034718
Release Date 2025-02-18
Submitter Yiming Zhou (zhouym35@mail.sysu.edu.cn)
Organization The First Affiliated Hospital, Sun Yat-sen University
Submission Date 2025-01-16
2Files & Download

The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.

File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX008711-01 Single-cell RNA seq expression matrix 3 Expression Profiling 53.53 MB rar Unavailable
OMIX008711-02 Ramos cell co-cultured with CCT128930 or DMSO bulk RNA seq expression matrix 1 Expression Profiling 721.74 KB csv Unavailable
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
TCL1A in naïve B cells as a therapeutic target for type 1 diabetes EBioMedicine 2025-02 OMIX008711 Deposit

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