| Title | scRNA-seq and spatial transcriptomics of HNSCC |
|---|---|
| Description | single-cell RNA sequencing (scRNA-seq) of whole tumor cells and paired scRNA-seq combining single-cell T/B cell receptor sequencing (scTCR/BCR-seq) of CD45+ cells in tumor, as well as spatial transcriptomics of tumor tissue sourced from HNSCC |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA025983 |
| Release Date | 2025-03-23 |
| Submitter | Zhijun Sun (zhijundejia@163.com) |
| Organization | Wuhan University |
| Submission Date | 2025-03-16 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX009480-01 | scRNA-seq for HNSCC | 14 | Expression Profiling | 2.08 GB | zip | |
| OMIX009480-02 | Paired scRNA-seq and scTCR/BCR-seq for HNSCC | 13 | Expression Profiling | 1.92 GB | zip | |
| OMIX009480-03 | Spatial transcriptomic sequencing for HNSCC | 10 | Expression Profiling | 143.43 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma | Cell Death & Disease | 2025-12 | OMIX009480 | Secondary use |
| Mature tertiary lymphoid structures evoke intra-tumoral T and B cell responses via progenitor exhausted CD4+ T cells in head and neck cancer | Nature Communications | 2025-05 | OMIX009480 | Deposit |