OMIX009638

1Summary
Title lipid metabolism
Description To optimize squalene retention, we systematically engineered membrane morphology and modified lipid metabolism. Compared with the control group, different lipid subclasses exhibited characteristic changes, overexpression of plsC, murG, and clsC significantly elevated phosphatidylethanolamine (PE) content; in contrast, overexpression of dgs led to a marked decrease in PE levels with a concurrent substantial increase in FA content, accounting for 95 % of the total lipid increment.
Organism Escherichia coli
Data Type Lipidome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA038058
Release Date 2025-07-26
Submitter Jiangming Zhu (zhujiangming@cemps.ac.cn)
Organization CAS Center for Excellence in Molecular Plant Sciences / Institute of Plant Physiology and Ecology
Submission Date 2025-04-01
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX009638-01 Absolute Quantitative lipidomome for lipid metabolism. 1 Lipidome Data by Mass Spectrometry (MS) 173.1 KB xlsx
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Metabolic engineering of Escherichia coli for squalene overproduction Synthetic and Systems Biotechnology 2025-06 OMIX009638 Deposit

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