| Title | Therapeutic Effects of Isaria felina on Postmenopausal Osteoporosis: Modulation of Gut Microbiota, Metabolites, and Immune Responses |
|---|---|
| Description | The effects of Isaria felina, derived from Cordyceps sinensis, on postmenopausal osteoporosis in rats are the focus of this study. Adult female Sprague-Dawley rats were assigned to control, postmenopausal osteoporosis (OVX) and Isaria felina-treated (IF+OVX) groups. Following a 12-week treatment period, various analyses, including micro-CT, histological assessments, 16S rDNA sequencing, untargeted metabolomics, flow cytometry and ELISA, were performed. |
| Organism | Rattus norvegicus |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA038081 |
| Release Date | 2025-04-03 |
| Submitter | Xiaochen Qiao (qxc2008441@163.com) |
| Organization | Second Hospital of Shanxi Medical University |
| Submission Date | 2025-04-01 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX009643-01 | Sample Group | 0 | Metabolome Data by Mass Spectrometry (MS) | 9.16 KB | xlsx | |
| OMIX009643-02 | QC postive ion mode raw data | 5 | Metabolome Data by Mass Spectrometry (MS) | 157.93 MB | zip | |
| OMIX009643-03 | postive ion mode raw data | 28 | Metabolome Data by Mass Spectrometry (MS) | 891.53 MB | zip | |
| OMIX009643-04 | negitive ion mode raw data | 28 | Metabolome Data by Mass Spectrometry (MS) | 871.43 MB | zip | |
| OMIX009643-05 | QC negitive ion mode raw data | 5 | Metabolome Data by Mass Spectrometry (MS) | 154.17 MB | zip | |
| OMIX009643-06 | postive ion mode wiff | 33 | Metabolome Data by Mass Spectrometry (MS) | 10.22 MB | zip | |
| OMIX009643-07 | negitive ion mode wiff | 33 | Metabolome Data by Mass Spectrometry (MS) | 10 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Therapeutic effects of Isaria felina on postmenopausal osteoporosis: modulation of gut microbiota, metabolites, and immune responses | Frontiers in Immunology | 2025-04 | OMIX009643 | Deposit |