OMIX010194

1Summary

Title	Integrative analyses of 16S rDNA sequencing and serum metabolomics demonstrates significant roles for the oral microbiota and serum metabolites in post-kidney transplant diabetes mellitus
Description	Oral microbiota and serum metabolites play crucial roles in diabetes, but their relationship with post-transplant diabetes mellitus (PTDM), a common complication post-kidney transplantation, is not well characterized. This study investigated the relationship of oral microbiota and serum metabolites with PTDM using integrative analysis of 16S rDNA sequencing and serum metabolomics.We recruited 61 kidney transplant recipients, including 30 in the PTDM group and 31 as normal glucose tolerance controls. Oral samples and serum samples were collected from all the kidney transplant patients to perform 16S rDNA sequencing and serum metabolomics analysis.
Organism	Homo sapiens
Data Type	Metabolome Data by Mass Spectrometry (MS)
Data Accessibility	Open-access
BioProject	PRJCA040184
Release Date	2025-06-03
Submitter	Chao Liu (m18286646384@163.com)
Organization	The Affiliated Hospital of Guizhou Medical University
Submission Date	2025-05-15

2Files & Download

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File ID	File Title	Number/Samples	File Type	File Size	File Suffix	Download
OMIX010194-01	neg_C26	1	Metabolome Data by Mass Spectrometry (MS)	53.93 MB	raw	FTP HTTPs
OMIX010194-02	neg_A09	1	Metabolome Data by Mass Spectrometry (MS)	56.7 MB	raw	FTP HTTPs
OMIX010194-03	neg_A22	1	Metabolome Data by Mass Spectrometry (MS)	57.2 MB	raw	FTP HTTPs
OMIX010194-04	neg_C7	1	Metabolome Data by Mass Spectrometry (MS)	55.49 MB	raw	FTP HTTPs
OMIX010194-05	neg_A26	1	Metabolome Data by Mass Spectrometry (MS)	57.14 MB	raw	FTP HTTPs
OMIX010194-06	pos_C31	1	Metabolome Data by Mass Spectrometry (MS)	73.02 MB	raw	FTP HTTPs
OMIX010194-07	neg_C15	1	Metabolome Data by Mass Spectrometry (MS)	55.29 MB	raw	FTP HTTPs
OMIX010194-08	neg_C20	1	Metabolome Data by Mass Spectrometry (MS)	56.96 MB	raw	FTP HTTPs
OMIX010194-09	neg_A01	1	Metabolome Data by Mass Spectrometry (MS)	59.68 MB	raw	FTP HTTPs
OMIX010194-10	neg_A03	1	Metabolome Data by Mass Spectrometry (MS)	57.52 MB	raw	FTP HTTPs
OMIX010194-11	neg_C27	1	Metabolome Data by Mass Spectrometry (MS)	55.44 MB	raw	FTP HTTPs
OMIX010194-12	pos_C17	1	Metabolome Data by Mass Spectrometry (MS)	73.92 MB	raw	FTP HTTPs
OMIX010194-13	neg_A04	1	Metabolome Data by Mass Spectrometry (MS)	56.44 MB	raw	FTP HTTPs
OMIX010194-14	pos_A09	1	Metabolome Data by Mass Spectrometry (MS)	73.81 MB	raw	FTP HTTPs
OMIX010194-15	pos_A22	1	Metabolome Data by Mass Spectrometry (MS)	72.61 MB	raw	FTP HTTPs
OMIX010194-16	neg_A24	1	Metabolome Data by Mass Spectrometry (MS)	56.4 MB	raw	FTP HTTPs
OMIX010194-17	neg_A17	1	Metabolome Data by Mass Spectrometry (MS)	54.12 MB	raw	FTP HTTPs
OMIX010194-18	neg_C24	1	Metabolome Data by Mass Spectrometry (MS)	57.65 MB	raw	FTP HTTPs
OMIX010194-19	pos_C15	1	Metabolome Data by Mass Spectrometry (MS)	73.62 MB	raw	FTP HTTPs
OMIX010194-20	neg_C14	1	Metabolome Data by Mass Spectrometry (MS)	55.15 MB	raw	FTP HTTPs
OMIX010194-21	pos_A13	1	Metabolome Data by Mass Spectrometry (MS)	74.09 MB	raw	FTP HTTPs
OMIX010194-22	pos_C20	1	Metabolome Data by Mass Spectrometry (MS)	77 MB	raw	FTP HTTPs
OMIX010194-23	neg_C17	1	Metabolome Data by Mass Spectrometry (MS)	56.56 MB	raw	FTP HTTPs
OMIX010194-24	neg_A29	1	Metabolome Data by Mass Spectrometry (MS)	55.59 MB	raw	FTP HTTPs
OMIX010194-25	neg_A02	1	Metabolome Data by Mass Spectrometry (MS)	58.29 MB	raw	FTP HTTPs
OMIX010194-26	pos_C24	1	Metabolome Data by Mass Spectrometry (MS)	76.94 MB	raw	FTP HTTPs
OMIX010194-27	pos_C7	1	Metabolome Data by Mass Spectrometry (MS)	74.22 MB	raw	FTP HTTPs
OMIX010194-28	neg_A15	1	Metabolome Data by Mass Spectrometry (MS)	53.49 MB	raw	FTP HTTPs
OMIX010194-29	pos_A08	1	Metabolome Data by Mass Spectrometry (MS)	73.85 MB	raw	FTP HTTPs
OMIX010194-30	pos_A16	1	Metabolome Data by Mass Spectrometry (MS)	72.62 MB	raw	FTP HTTPs
OMIX010194-31	neg_A08	1	Metabolome Data by Mass Spectrometry (MS)	56.8 MB	raw	FTP HTTPs
OMIX010194-32	neg_C31	1	Metabolome Data by Mass Spectrometry (MS)	56.2 MB	raw	FTP HTTPs
OMIX010194-33	pos_C2	1	Metabolome Data by Mass Spectrometry (MS)	72.92 MB	raw	FTP HTTPs
OMIX010194-34	pos_C16	1	Metabolome Data by Mass Spectrometry (MS)	74.82 MB	raw	FTP HTTPs
OMIX010194-35	neg_C10	1	Metabolome Data by Mass Spectrometry (MS)	56.01 MB	raw	FTP HTTPs
OMIX010194-36	neg_C22	1	Metabolome Data by Mass Spectrometry (MS)	57.87 MB	raw	FTP HTTPs
OMIX010194-37	pos_C29	1	Metabolome Data by Mass Spectrometry (MS)	77.18 MB	raw	FTP HTTPs
OMIX010194-38	neg_A14	1	Metabolome Data by Mass Spectrometry (MS)	52.51 MB	raw	FTP HTTPs
OMIX010194-39	pos_C21	1	Metabolome Data by Mass Spectrometry (MS)	76.03 MB	raw	FTP HTTPs
OMIX010194-40	pos_C3	1	Metabolome Data by Mass Spectrometry (MS)	75.94 MB	raw	FTP HTTPs
OMIX010194-41	neg_A25	1	Metabolome Data by Mass Spectrometry (MS)	56.83 MB	raw	FTP HTTPs
OMIX010194-42	neg_C4	1	Metabolome Data by Mass Spectrometry (MS)	55.91 MB	raw	FTP HTTPs
OMIX010194-43	pos_A03	1	Metabolome Data by Mass Spectrometry (MS)	74.69 MB	raw	FTP HTTPs
OMIX010194-44	pos_C19	1	Metabolome Data by Mass Spectrometry (MS)	74.35 MB	raw	FTP HTTPs
OMIX010194-45	pos_A21	1	Metabolome Data by Mass Spectrometry (MS)	73.83 MB	raw	FTP HTTPs
OMIX010194-46	neg_C18	1	Metabolome Data by Mass Spectrometry (MS)	57.17 MB	raw	FTP HTTPs
OMIX010194-47	neg_A06	1	Metabolome Data by Mass Spectrometry (MS)	56.43 MB	raw	FTP HTTPs
OMIX010194-48	neg_C9	1	Metabolome Data by Mass Spectrometry (MS)	57.7 MB	raw	FTP HTTPs
OMIX010194-49	pos_A24	1	Metabolome Data by Mass Spectrometry (MS)	73.91 MB	raw	FTP HTTPs
OMIX010194-50	neg_A21	1	Metabolome Data by Mass Spectrometry (MS)	54.29 MB	raw	FTP HTTPs
OMIX010194-51	neg_A20	1	Metabolome Data by Mass Spectrometry (MS)	58.78 MB	raw	FTP HTTPs
OMIX010194-52	pos_C1	1	Metabolome Data by Mass Spectrometry (MS)	76.82 MB	raw	FTP HTTPs
OMIX010194-53	neg_A30	1	Metabolome Data by Mass Spectrometry (MS)	59.45 MB	raw	FTP HTTPs
OMIX010194-54	pos_A11	1	Metabolome Data by Mass Spectrometry (MS)	72.38 MB	raw	FTP HTTPs
OMIX010194-55	pos_C25	1	Metabolome Data by Mass Spectrometry (MS)	72.63 MB	raw	FTP HTTPs
OMIX010194-56	pos_C13	1	Metabolome Data by Mass Spectrometry (MS)	74.16 MB	raw	FTP HTTPs
OMIX010194-57	pos_A23	1	Metabolome Data by Mass Spectrometry (MS)	73.34 MB	raw	FTP HTTPs
OMIX010194-58	pos_A14	1	Metabolome Data by Mass Spectrometry (MS)	74.1 MB	raw	FTP HTTPs
OMIX010194-59	pos_A30	1	Metabolome Data by Mass Spectrometry (MS)	77.37 MB	raw	FTP HTTPs
OMIX010194-60	neg_A12	1	Metabolome Data by Mass Spectrometry (MS)	55.18 MB	raw	FTP HTTPs
OMIX010194-61	neg_C30	1	Metabolome Data by Mass Spectrometry (MS)	57.5 MB	raw	FTP HTTPs
OMIX010194-62	pos_C18	1	Metabolome Data by Mass Spectrometry (MS)	74.42 MB	raw	FTP HTTPs
OMIX010194-63	pos_C5	1	Metabolome Data by Mass Spectrometry (MS)	76.08 MB	raw	FTP HTTPs
OMIX010194-64	pos_C28	1	Metabolome Data by Mass Spectrometry (MS)	75.77 MB	raw	FTP HTTPs
OMIX010194-65	pos_A07	1	Metabolome Data by Mass Spectrometry (MS)	74.32 MB	raw	FTP HTTPs
OMIX010194-66	pos_A17	1	Metabolome Data by Mass Spectrometry (MS)	74.36 MB	raw	FTP HTTPs
OMIX010194-67	pos_C4	1	Metabolome Data by Mass Spectrometry (MS)	76.16 MB	raw	FTP HTTPs
OMIX010194-68	pos_A12	1	Metabolome Data by Mass Spectrometry (MS)	72.88 MB	raw	FTP HTTPs
OMIX010194-69	pos_C22	1	Metabolome Data by Mass Spectrometry (MS)	76.81 MB	raw	FTP HTTPs
OMIX010194-70	neg_A19	1	Metabolome Data by Mass Spectrometry (MS)	53.77 MB	raw	FTP HTTPs
OMIX010194-71	neg_A10	1	Metabolome Data by Mass Spectrometry (MS)	56.31 MB	raw	FTP HTTPs
OMIX010194-72	neg_A16	1	Metabolome Data by Mass Spectrometry (MS)	54.95 MB	raw	FTP HTTPs
OMIX010194-73	neg_C5	1	Metabolome Data by Mass Spectrometry (MS)	57.41 MB	raw	FTP HTTPs
OMIX010194-74	pos_A29	1	Metabolome Data by Mass Spectrometry (MS)	76.71 MB	raw	FTP HTTPs
OMIX010194-75	neg_C16	1	Metabolome Data by Mass Spectrometry (MS)	57.49 MB	raw	FTP HTTPs
OMIX010194-76	neg_C6	1	Metabolome Data by Mass Spectrometry (MS)	56.44 MB	raw	FTP HTTPs
OMIX010194-77	pos_C9	1	Metabolome Data by Mass Spectrometry (MS)	73.16 MB	raw	FTP HTTPs
OMIX010194-78	pos_C26	1	Metabolome Data by Mass Spectrometry (MS)	74.61 MB	raw	FTP HTTPs
OMIX010194-79	neg_C3	1	Metabolome Data by Mass Spectrometry (MS)	56.39 MB	raw	FTP HTTPs
OMIX010194-80	pos_C10	1	Metabolome Data by Mass Spectrometry (MS)	72.4 MB	raw	FTP HTTPs
OMIX010194-81	pos_C6	1	Metabolome Data by Mass Spectrometry (MS)	75.56 MB	raw	FTP HTTPs
OMIX010194-82	pos_A20	1	Metabolome Data by Mass Spectrometry (MS)	76.62 MB	raw	FTP HTTPs
OMIX010194-83	neg_C25	1	Metabolome Data by Mass Spectrometry (MS)	54.6 MB	raw	FTP HTTPs
OMIX010194-84	neg_A28	1	Metabolome Data by Mass Spectrometry (MS)	55.59 MB	raw	FTP HTTPs
OMIX010194-85	pos_A18	1	Metabolome Data by Mass Spectrometry (MS)	75.06 MB	raw	FTP HTTPs
OMIX010194-86	pos_A19	1	Metabolome Data by Mass Spectrometry (MS)	73.92 MB	raw	FTP HTTPs
OMIX010194-87	neg_C19	1	Metabolome Data by Mass Spectrometry (MS)	57.29 MB	raw	FTP HTTPs
OMIX010194-88	neg_C13	1	Metabolome Data by Mass Spectrometry (MS)	56.42 MB	raw	FTP HTTPs
OMIX010194-89	neg_C12	1	Metabolome Data by Mass Spectrometry (MS)	54.77 MB	raw	FTP HTTPs
OMIX010194-90	neg_A07	1	Metabolome Data by Mass Spectrometry (MS)	58.84 MB	raw	FTP HTTPs
OMIX010194-91	pos_C11	1	Metabolome Data by Mass Spectrometry (MS)	74.32 MB	raw	FTP HTTPs
OMIX010194-92	pos_A04	1	Metabolome Data by Mass Spectrometry (MS)	75.97 MB	raw	FTP HTTPs
OMIX010194-93	pos_A26	1	Metabolome Data by Mass Spectrometry (MS)	75.6 MB	raw	FTP HTTPs
OMIX010194-94	pos_A01	1	Metabolome Data by Mass Spectrometry (MS)	77.47 MB	raw	FTP HTTPs
OMIX010194-95	pos_C27	1	Metabolome Data by Mass Spectrometry (MS)	72.93 MB	raw	FTP HTTPs
OMIX010194-96	neg_A05	1	Metabolome Data by Mass Spectrometry (MS)	58.99 MB	raw	FTP HTTPs
OMIX010194-97	pos_C8	1	Metabolome Data by Mass Spectrometry (MS)	74.84 MB	raw	FTP HTTPs
OMIX010194-98	neg_A18	1	Metabolome Data by Mass Spectrometry (MS)	56.03 MB	raw	FTP HTTPs
OMIX010194-99	neg_A11	1	Metabolome Data by Mass Spectrometry (MS)	55.3 MB	raw	FTP HTTPs
OMIX010194-100	neg_C29	1	Metabolome Data by Mass Spectrometry (MS)	57.99 MB	raw	FTP HTTPs
OMIX010194-101	neg_C21	1	Metabolome Data by Mass Spectrometry (MS)	56.58 MB	raw	FTP HTTPs
OMIX010194-102	pos_C23	1	Metabolome Data by Mass Spectrometry (MS)	76.19 MB	raw	FTP HTTPs
OMIX010194-103	pos_C14	1	Metabolome Data by Mass Spectrometry (MS)	72.95 MB	raw	FTP HTTPs
OMIX010194-104	neg_A13	1	Metabolome Data by Mass Spectrometry (MS)	54.82 MB	raw	FTP HTTPs
OMIX010194-105	pos_A02	1	Metabolome Data by Mass Spectrometry (MS)	76.42 MB	raw	FTP HTTPs
OMIX010194-106	neg_C23	1	Metabolome Data by Mass Spectrometry (MS)	58.25 MB	raw	FTP HTTPs
OMIX010194-107	pos_A10	1	Metabolome Data by Mass Spectrometry (MS)	74.92 MB	raw	FTP HTTPs
OMIX010194-108	pos_A25	1	Metabolome Data by Mass Spectrometry (MS)	74.5 MB	raw	FTP HTTPs
OMIX010194-109	pos_A05	1	Metabolome Data by Mass Spectrometry (MS)	76.76 MB	raw	FTP HTTPs
OMIX010194-110	neg_A27	1	Metabolome Data by Mass Spectrometry (MS)	57.29 MB	raw	FTP HTTPs
OMIX010194-111	neg_C2	1	Metabolome Data by Mass Spectrometry (MS)	58.22 MB	raw	FTP HTTPs
OMIX010194-112	neg_C8	1	Metabolome Data by Mass Spectrometry (MS)	57.78 MB	raw	FTP HTTPs
OMIX010194-113	neg_A23	1	Metabolome Data by Mass Spectrometry (MS)	55.21 MB	raw	FTP HTTPs
OMIX010194-114	pos_C12	1	Metabolome Data by Mass Spectrometry (MS)	73.23 MB	raw	FTP HTTPs
OMIX010194-115	neg_C11	1	Metabolome Data by Mass Spectrometry (MS)	53.02 MB	raw	FTP HTTPs
OMIX010194-116	pos_C30	1	Metabolome Data by Mass Spectrometry (MS)	74.87 MB	raw	FTP HTTPs
OMIX010194-117	pos_A15	1	Metabolome Data by Mass Spectrometry (MS)	72.96 MB	raw	FTP HTTPs
OMIX010194-118	pos_A28	1	Metabolome Data by Mass Spectrometry (MS)	75.92 MB	raw	FTP HTTPs
OMIX010194-119	pos_A06	1	Metabolome Data by Mass Spectrometry (MS)	77.22 MB	raw	FTP HTTPs
OMIX010194-120	neg_C28	1	Metabolome Data by Mass Spectrometry (MS)	59.18 MB	raw	FTP HTTPs
OMIX010194-121	pos_A27	1	Metabolome Data by Mass Spectrometry (MS)	74.85 MB	raw	FTP HTTPs
OMIX010194-122	neg_C1	1	Metabolome Data by Mass Spectrometry (MS)	57.89 MB	raw	FTP HTTPs

3Relevant Publications

Paper Title	Journal Name	Publish Time	Accession	Citing Type
Integrative analyses of 16S rDNA sequencing and serum metabolomics demonstrate significant roles for the oral microbiota and serum metabolites in post-kidney …	Microbiology Spectrum	2025-06	OMIX010194	Deposit

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