OMIX010582

1Summary

Title	Betaine alleviates obesity-related metabolic disorders in rats: insights from microbiomes, lipidomics, and transcriptomics
Description	Betaine is a natural food component that plays an important role in improving body composition, but the details of its effects on adipose tissue remains to be elucidated. Here, we hypothesize that betaine can alleviate obesity-related metabolic disorders, thus gut microbiota, transcriptomics and lipidomics were used to investigate the obesity-alleviating effects of betaine on high-fat diet (HFD)-fed rats. Our findings imply that the supplementation of betaine can diminish the accumulation of lipid in visceral adipose tissue, thereby improving dyslipidemia and leptin resistance.
Organism	Rattus norvegicus
Data Type	Lipidome Data by Mass Spectrometry (MS)
Data Accessibility	Open-access
BioProject	PRJCA041580
Release Date	2025-07-02
Submitter	Xian Wang (13783515250@139.com)
Organization	The First Affiliated Hospital of Henan University of Chinese Medicine
Submission Date	2025-06-13

2Files & Download

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File ID	File Title	Number/Samples	File Type	File Size	File Suffix	Download
OMIX010582-01	1 POS_Gg17SX_M_4.raw	1	Lipidome Data by Mass Spectrometry (MS)	91.76 MB	raw	FTP HTTPs
OMIX010582-02	NEG_Gg17SX_M_4.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.99 MB	raw	FTP HTTPs
OMIX010582-03	NEG_Gg17SX_M_5.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.56 MB	raw	FTP HTTPs
OMIX010582-04	NEG_Gg17SX_C3.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.42 MB	raw	FTP HTTPs
OMIX010582-05	POS_Gg17SX_C1.raw	1	Lipidome Data by Mass Spectrometry (MS)	95.79 MB	raw	FTP HTTPs
OMIX010582-06	POS_Gg17SX_C4.raw	1	Lipidome Data by Mass Spectrometry (MS)	95.5 MB	raw	FTP HTTPs
OMIX010582-07	POS_Gg14SX_T1.raw	1	Lipidome Data by Mass Spectrometry (MS)	92.53 MB	raw	FTP HTTPs
OMIX010582-08	POS_Gg17SX_M_3.raw	1	Lipidome Data by Mass Spectrometry (MS)	91.8 MB	raw	FTP HTTPs
OMIX010582-09	POS_Gg17SX_M_2.raw	1	Lipidome Data by Mass Spectrometry (MS)	91.95 MB	raw	FTP HTTPs
OMIX010582-10	NEG_Gg14SX_T6.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.35 MB	raw	FTP HTTPs
OMIX010582-11	POS_Gg17SX_M1_1.raw	1	Lipidome Data by Mass Spectrometry (MS)	92.11 MB	raw	FTP HTTPs
OMIX010582-12	NEG_Gg14SX_T5.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.57 MB	raw	FTP HTTPs
OMIX010582-13	POS_Gg17SX_C6.raw	1	Lipidome Data by Mass Spectrometry (MS)	94.5 MB	raw	FTP HTTPs
OMIX010582-14	NEG_Gg17SX_C5.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.74 MB	raw	FTP HTTPs
OMIX010582-15	NEG_Gg17SX_M_6.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.43 MB	raw	FTP HTTPs
OMIX010582-16	POS_Gg14SX_T3.raw	1	Lipidome Data by Mass Spectrometry (MS)	93.49 MB	raw	FTP HTTPs
OMIX010582-17	POS_Gg14SX_T5.raw	1	Lipidome Data by Mass Spectrometry (MS)	92.69 MB	raw	FTP HTTPs
OMIX010582-18	NEG_Gg17SX_M1_1.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.98 MB	raw	FTP HTTPs
OMIX010582-19	NEG_Gg17SX_C6.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.55 MB	raw	FTP HTTPs
OMIX010582-20	POS_Gg14SX_T4.raw	1	Lipidome Data by Mass Spectrometry (MS)	93.1 MB	raw	FTP HTTPs
OMIX010582-21	NEG_Gg14SX_T2.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.2 MB	raw	FTP HTTPs
OMIX010582-22	NEG_Gg14SX_T1.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.51 MB	raw	FTP HTTPs
OMIX010582-23	POS_Gg14SX_T2.raw	1	Lipidome Data by Mass Spectrometry (MS)	93.21 MB	raw	FTP HTTPs
OMIX010582-24	POS_Gg17SX_M_6.raw	1	Lipidome Data by Mass Spectrometry (MS)	92.04 MB	raw	FTP HTTPs
OMIX010582-25	NEG_Gg14SX_T4.raw	1	Lipidome Data by Mass Spectrometry (MS)	83 MB	raw	FTP HTTPs
OMIX010582-26	POS_Gg17SX_C3.raw	1	Lipidome Data by Mass Spectrometry (MS)	94.98 MB	raw	FTP HTTPs
OMIX010582-27	POS_Gg17SX_C5.raw	1	Lipidome Data by Mass Spectrometry (MS)	95.36 MB	raw	FTP HTTPs
OMIX010582-28	NEG_Gg14SX_T3.raw	1	Lipidome Data by Mass Spectrometry (MS)	82.89 MB	raw	FTP HTTPs
OMIX010582-29	POS_Gg17SX_M_5.raw	1	Lipidome Data by Mass Spectrometry (MS)	91.73 MB	raw	FTP HTTPs
OMIX010582-30	POS_Gg17SX_C7.raw	1	Lipidome Data by Mass Spectrometry (MS)	95.5 MB	raw	FTP HTTPs
OMIX010582-31	NEG_Gg17SX_C4.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.04 MB	raw	FTP HTTPs
OMIX010582-32	NEG_Gg17SX_C7.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.49 MB	raw	FTP HTTPs
OMIX010582-33	NEG_Gg17SX_M_2.raw	1	Lipidome Data by Mass Spectrometry (MS)	84.03 MB	raw	FTP HTTPs
OMIX010582-34	POS_Gg14SX_T6.raw	1	Lipidome Data by Mass Spectrometry (MS)	93.15 MB	raw	FTP HTTPs
OMIX010582-35	NEG_Gg17SX_C1.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.65 MB	raw	FTP HTTPs
OMIX010582-36	NEG_Gg17SX_M_3.raw	1	Lipidome Data by Mass Spectrometry (MS)	83.67 MB	raw	FTP HTTPs

3Relevant Publications

Paper Title	Journal Name	Publish Time	Accession	Citing Type
Betaine alleviates obesity-related metabolic disorders in rats: insights from microbiomes, lipidomics, and transcriptomics	Frontiers in Nutrition	2025-07	OMIX010582	Deposit

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