OMIX011057

1Summary
Title Metabolomic analysis of MIA PaCa-2 cells following SMIM4 depletion and malate supplementation under glucose-deficient conditions
Description Human pancreatic cancer cells (MIA PaCa-2) were analyzed after 24-hour treatments under glucose-deficient conditions (n=5 replicates/group): (1) shCtrl (non-targeting control, #1-5), (2) shSMIM4 knockdown (#6-10), (3) shCtrl+4mM malate (#11-15), and (4) shSMIM4+4mM malate (#16-20).
Organism Homo
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA043295
Release Date 2025-07-18
Submitter BO WANG (1577956313@qq.com)
Organization Wenzhou Medical University
Submission Date 2025-07-16
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX011057-01 Metabolomics_Data_2 20 Metabolome Data by Mass Spectrometry (MS) 667.83 MB rar
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
The integral membrane protein smim4 modulates redox balance via malate compartmentalization in pancreatic cancer Nature Communications 2025-11 OMIX011057 OMIX011055 Deposit

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