| Title | Remodeling adipocytes lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow |
|---|---|
| Description | The function of osteoporosis-induced bone marrow adipocyte (BMAds) accumulation remains inadequately understood. Here, we analyze bone marrow lipidomic data and reveal that BMAds deteriorate the skeletal microenvironment by secreting large amounts of lipids, altering the senescence status of neighboring cells by affecting their mitochondrial function. |
| Organism | Mus musculus |
| Data Type | Lipidome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA043791 |
| Release Date | 2025-08-13 |
| Submitter | Wenzheng Lin (m13415146506@163.com) |
| Organization | Yangzhou University |
| Submission Date | 2025-07-26 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX011181-01 | FW2024-521 | 4 | Lipidome Data by Mass Spectrometry (MS) | 3.5 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Remodeling adipocytes' lipid metabolism with a polycation loaded enzyme-active framework reverses osteoporotic bone marrow | Nature Communications | 2025-08 | OMIX011181 | Deposit |