OMIX011442

1Summary
Title bulk RNA-seq data of MFE-2 cKO microglia
Description To understand the inflammatory status of MFE-2 cKO microglia, we conducted bulk RNA-seq of FACS-sorted microglia from 4-month-old Flox and MFE-2 cKO mouse brains. The differentially expressed genes identified via gene set enrichment analysis (GSEA) were closely related to IL-6 pathways
Organism Mus
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA027327
Release Date 2025-08-14
Submitter Honglin Wang (honglin.wang@sjtu.edu.cn)
Organization Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (SJTU-SM),
Submission Date 2025-08-13
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX011442-01 bulk RNA-seq data of MFE-2 cKO microglia 1 Expression Profiling 3.6 MB xlsx
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Loss of MFE-2 impairs microglial lipid homeostasis and drives neuroinflammation in Alzheimer's pathogenesis Nature Aging 2025-11 OMIX011442 Deposit

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