| Title | RNA-seq profiling of the mycelia of Magnaporthe oryzae wild-type (70-15) and mutants (Moclr4, Mocul4) in complete medium (CM). |
|---|---|
| Description | Rice blast, caused by the fungal pathogen Magnaporthe oryzae, poses a severe threat to global rice production security. As a model organism for studying molecular pathogenesis in filamentous fungi and host-pathogen interactions, M. oryzae exhibits a characteristic life cycle and infection process. Autophagy is essential for the growth, sporulation, and pathogenicity of M. oryzae. MoClr4 is a histone H3K9 methyltransferase in the rice blast fungus Magnaporthe oryzae. MoCul4 interacts with MoClr4 and regulates its methyltransferase activity. In this study, we constructed knockout mutants of the target genes via homologous recombination and analyzed the differentially expressed genes (DEGs) of the mutants cultured in complete medium (CM). Furthermore, we found that MoRph1, an H3K36 demethylase which participates in autophagy, influences the expression profile of these mutants. |
| Organism | Pyricularia oryzae |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA041989 |
| Release Date | 2025-09-25 |
| Submitter | Pengyun Huang (huangpengyun2012@163.com) |
| Organization | Linyi University |
| Submission Date | 2025-09-24 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX012048-01 | Different expression | 3 | Expression Profiling | 2.1 MB | zip | |
| OMIX012048-02 | KOG Functional Categories of Moclr4 and Mocul4 mutants | 2 | Expression Profiling | 13.5 KB | zip | |
| OMIX012048-03 | Glucanase gene expression level of Mocul4 and Moclr4 | 2 | Expression Profiling | 10.7 KB | xlsx | |
| OMIX012048-04 | KO and KEGG enrichment | 3 | Expression Profiling | 125.7 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| MoCul4 assists MoKmt1 to catalyze H3K9 methylation and regulates the growth, development, and pathogenicity in Magnaporthe oryzae | Virulence | 2026-09 | OMIX012048 | Deposit |