| Title | Proteomic Profiling of Extracellular Vesicles Derived from hTERT-Immortalized Human Placental Chorionic Mesenchymal Stromal Cells |
|---|---|
| Description | This study provides proteomic data of extracellular vesicles derived from hTERT-immortalized human placental chorionic mesenchymal stromal cells , with EVs from primary placental chorionic mesenchymal stromal cells as control. Extracellular vesicles were characterized and analyzed by LC-MS/MS. Among 1,982 identified proteins, 445 differentially expressed proteins were found , despite high overall similarity.GO analysis revealed differentially expressed proteins involvement in ribosome biogenesis, translation, collagen organization, and cell adhesion. KEGG enrichment highlighted associations with PI3K-Akt signaling, ECM-receptor interaction, and disease-related pathways. |
| Organism | Homo sapiens |
| Data Type | Proteomic Data by Mass Spectrometry (MS) |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA046720 |
| Release Date | 2025-09-29 |
| Submitter | guanghua yang (fulreak@126.com) |
| Organization | Shanghai Ocean University |
| Submission Date | 2025-09-25 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX012060-04 | MSC-EV1-VS-MSCA-EV1 | 2 | Proteomic Data by Mass Spectrometry (MS) | 23.76 GB | tar | Controlled |
| OMIX012060-05 | MSC-EV2-VS-MSCA-EV2 | 1 | Proteomic Data by Mass Spectrometry (MS) | 2.17 GB | tar | Controlled |
| OMIX012060-06 | MSC-EV3-VS-MSCA-EV3 | 1 | Proteomic Data by Mass Spectrometry (MS) | 1.43 MB | tar | Controlled |