| Title | Untargeted metabolomic analysis of dietary rumen-protected choline supplementation in fattening lambs |
|---|---|
| Description | This study investigated the effects of rumen-protected choline (RPC) supplementation on serum metabolite profiles in fattening lambs. Twenty 3-month-old hybrid rams were randomly assigned to two groups: a control group and an RPC group. Serum samples were collected at the end of the trial and analyzed using untargeted metabolomics based on liquid chromatography-tandem mass spectrometry. A wide range of metabolites were identified, including benzenoids, lipids and lipid-like molecules, nucleosides and nucleotides, organic acids, and derivatives. Pathway analysis using the KEGG revealed involvement in lipid, amino acid, vitamin, and carbohydrate metabolism. PLS-DA showed clear separation between CON and RPC groups. RPC supplementation significantly modulated the serum metabolome, enhancing HCW and slaughter rate, likely via lipid, amino acid, and energy metabolism pathways. |
| Organism | Ovis aries |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA047602 |
| Release Date | 2025-10-15 |
| Submitter | Jinyan Yun (yunjinyan888@jlnku.edu.cn) |
| Organization | Jilin Agricultural Science and Technology College |
| Submission Date | 2025-10-09 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX012211-01 | negative.rar | 1 | Metabolome Data by Mass Spectrometry (MS) | 723.02 MB | rar | |
| OMIX012211-03 | positive raw file | 50 | Metabolome Data by Mass Spectrometry (MS) | 705.03 MB | rar | |
| OMIX012211-04 | negative raw file | 50 | Metabolome Data by Mass Spectrometry (MS) | 723.02 MB | rar | |
| OMIX012211-09 | positiveMD5.rar | 1 | Metabolome Data by Mass Spectrometry (MS) | 108 bytes | rar |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Untargeted metabolomic analysis of dietary rumen-protected choline supplementation in fattening lambs | Frontiers in Veterinary Science | 2025-10 | OMIX012211 | Deposit |