| Title | Cytospora chrysosperma KMT3 ChiP-seq |
|---|---|
| Description | The histone lysine methyltransferase Kmt3 (CcKmt3) is induced by C. chrysosperma infection. Loss of Cckmt3 leads to a genome-wide reduction in H3K36me3 methylation. The ΔCckmt3 strain presented hyphal growth defects, reduced production of hydrolytic enzymes, and impaired virulence. By combining Chip-seq with RNA-seq, we demonstrated that CcKmt3 controls two hydrolases, CcLac11 and CcPme5, for plant cell degradation and virulence in C. chrysosperma. Furthermore, we showed that CcKmt3 affects hyphal growth by regulating the fungal cell wall integrity pathway. Taken together, the results of this study reveal an epigenetic mechanism by which CcKmt3 regulates CWDEs in plant cell wall degradation and pathogenesis in poplar canker fungus. |
| Organism | Valsa sordida |
| Data Type | Chromatin Accessibility Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA058710 |
| Release Date | 2026-02-24 |
| Submitter | Wenjun Song Song (S18854881889@163.com) |
| Organization | Beijing Forestry University |
| Submission Date | 2026-02-24 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX015268-01 | classified_genes | 2 | Chromatin Accessibility Profiling | 834.2 KB | csv | |
| OMIX015268-02 | significant | 2 | Chromatin Accessibility Profiling | 8.5 KB | CSV |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| The Methyltransferase Cc Kmt3 Regulates Cell Wall Degradation Enzymes Activity to Enhance the Infection Process in Cytospora chrysosperma | Molecular Plant Pathology | 2026-04 | OMIX015268 OMIX015267 | Deposit |