Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans
| Title | Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans |
|---|---|
| Description | To investigate endocrine lineage differentiation pathways in humans, we performed scRNA-seq of pancreatic cells from human embryos at 9-19 weeks post conception (W) using a modified STRT-seq (mSTRT-seq) method. We also performed 10x Genomics scRNA-seq of whole human pancreatic cells at W8-19, and enriched multipotent pancreatic progenitor and acinar cells (EpCAM+GP2+) and endocrine cells (EpCAM+GP2-) at W12. |
| Organism | Homo sapiens |
| Data Type | - |
| Data Accessibility | Open-access |
| BioProject | PRJCA004336 |
| Release Date | 2021-04-27 |
| Submitter | Cheng-Ran Xu (cxu@pku.edu.cn) |
| Organization | Peking University |
| Submission Date | 2021-02-05 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX236-20-01 | Human_mSTRTSeq.UMI.txt.gz | 21 | Transcriptomic | 24.7 MB | gz | 151 | |
| OMIX236-20-02 | Human_10x.UMI.txt.gz | 9 | Transcriptomic | 91.5 MB | gz | 293 | |
| OMIX236-99-03 | OMIX_gene_expression_profile.xlsx | 0 | others | 26.5 KB | xlsx | 126 |