| Description |
Keratoconus (KC) is an asymmetric, progressive ectasia that can lead to severe visual impairment. Despite the high prevalence of the disease, the molecular mechanisms underlying the disease are poorly understood. Here, we analyzed tissues from normal and KC corneas by m6a microarray. Our data showed that the level of m6a modification was significantly altered in cone corneas compared to controls, while KC showed increased inflammation. In conclusion, our corneal tissue data in steady state and disease states provide a unique resource for identifying genes that may contribute to KC and for better understanding and treatment of KC. |