Study of m6A methylation modification in the keratoconus
| Title | Study of m6A methylation modification in the keratoconus |
|---|---|
| Description | Keratoconus (KC) is an asymmetric, progressive ectasia that can lead to severe visual impairment. Despite the high prevalence of the disease, the molecular mechanisms underlying the disease are poorly understood. Here, we analyzed tissues from normal and KC corneas by m6a microarray. Our data showed that the level of m6a modification was significantly altered in cone corneas compared to controls, while KC showed increased inflammation. In conclusion, our corneal tissue data in steady state and disease states provide a unique resource for identifying genes that may contribute to KC and for better understanding and treatment of KC. |
| Organism | Homo |
| Data Type | RNA Microarray |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA005902 |
| Release Date | 2023-07-31 |
| Submitter | Hua Gao (hgao@sdfmu.edu.cn) |
| Organization | Shandong First Medical University |
| Submission Date | 2021-08-03 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX504-51-01 | raw data files | 10 | RNA Microarray | 56.9 MB | zip | 0 | Unavailable |