OMIX

Decipher unwinding mechanisms of RNA helicases MOV10 and MOV10L1

OMIX655

1Summary
Title Decipher unwinding mechanisms of RNA helicases MOV10 and MOV10L1
Description MOV10L1 and its paralog MOV10 are evolutionally conserved RNA helicases involved in distinct RNA regulatory pathways. We comprehensively characterized and compared the activities of these two helicases on various nucleic acid substrates in vitro, with a focus on RNA G-quadruplex (RG4) structure. We find that both MOV10L1 and MOV10 are able to resolve RG4, with MOV10L1 being more efficient in that.
Organism Mus
Data Type -
Data Accessibility Open-access
BioProject PRJCA006631
Release Date 2021-09-19
Submitter Xia Zhang (zhangxia@shanghaitech.edu.cn)
Organization ShanghaiTech University
Submission Date 2021-09-19
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX655-10-01 Decipher unwinding mechanisms of RNA helicases MOV10 and MOV10L1 67 Proteomic 174.49 MB rar 0

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