Provide a dynamic understanding of SaCas9 in DNA target association and dissociation.
| Title | Provide a dynamic understanding of SaCas9 in DNA target association and dissociation. |
|---|---|
| Description | Staphylococcus aureus Cas9 (SaCas9) is an endonuclease that has been widely repurposed for biological usages. Its small size facilitates in vivo delivery for genome editing in various organisms. Using single-molecule and ensemble approaches, we systemically studied the molecular mechanism of SaCas9 underlying its interplay with DNA. The dynamic understanding of SaCas9 will instruct its effective applications. |
| Organism | Staphylococcus aureus |
| Data Type | - |
| Data Accessibility | Open-access |
| BioProject | PRJCA006631 |
| Release Date | 2021-09-19 |
| Submitter | Xia Zhang (zhangxia@shanghaitech.edu.cn) |
| Organization | ShanghaiTech University |
| Submission Date | 2021-09-19 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX659-10-01 | Provide a dynamic understanding of SaCas9 in DNA target association and dissociation. | 9424 | Proteomic | 6.95 GB | rar | 0 |