Analysis of chromosome ploidy in infants with embryonic chromosomal mosaicism by single-cell multi-omics sequencing.
| Title | Analysis of chromosome ploidy in infants with embryonic chromosomal mosaicism by single-cell multi-omics sequencing. |
|---|---|
| Description | While knowing the consequence of embryonic chromosomal mosaicism is important for both IVF pregnancy and natural conception, postnatal evaluation of transferred mosaic embryos is not sufficient, which is mainly focused on the rates of pregnancy and birth, whereas data on high resolution postnatal karyotyping and chromosome testing are still lacking. Here we performed single-cell multi-omics sequencing for peripheral white blood cells obtained from 7 infants with embryonic chromosomal mosaicism to explore their chromosome ploidy status at single-cell resolution. |
| Organism | Homo sapiens |
| Data Type | - |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA007982 |
| Release Date | 2023-12-31 |
| Submitter | Fuchou Tang (tangfuchou@pku.edu.cn) |
| Organization | Peking University |
| Submission Date | 2022-01-21 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX910-99-01 | Statistics of single-cell CNV | 2208 | Genotype | 157.84 KB | csv | 0 | Controlled |
| OMIX910-99-02 | Estimated copy number of each cell at each genomic bin | 2208 | Genotype | 168.54 KB | csv | 0 | Controlled |
| OMIX910-20-03 | Summary of sequenced cells | 2208 | Transcriptomic | 173.36 KB | csv | 0 | Controlled |
| OMIX910-99-04 | Genomic bins for single cell CNV estimation | 2808 | Genotype | 91.78 KB | csv | 0 | Controlled |
| OMIX910-99-05 | Normalized read count of each cell at each genomic bin | 2208 | Genotype | 45.79 MB | csv | 0 | Controlled |
| OMIX910-99-06 | Results of CNV-Seq of TE PGC-A | 10 | Genotype | 357 B | csv | 0 | Controlled |
| OMIX910-20-07 | UMI count for single cell RNA-Seq | 2208 | Transcriptomic | 2.82 MB | csv | 0 | Controlled |