OMIX

Metagenomic Next-Generation Sequencing versus Traditional Pathogen Detection in the Diagnosis of Infection after Allogeneic Hematopoietic Stem Cell Transplantation in Children

OMIX974

1Summary
Title Metagenomic Next-Generation Sequencing versus Traditional Pathogen Detection in the Diagnosis of Infection after Allogeneic Hematopoietic Stem Cell Transplantation in Children
Description We compared metagenomic next-generation sequencing (mNGS) and traditional pathogen detection in investigating the pathogens of infections (such as bloodstream infections, pulmonary infections, and central nervous system (CNS) infections) in pediatric allo-HSCT recipients. This study retrospectively analyzed 101 pediatric recipients of allo-HSCT, including 54 bronchoalveolar lavage fluid samples, 32 blood samples, and 15 cerebrospinal fluid samples. Eighty-seven were diagnosed with post-transplant infectious diseases and 14 with non-infectious diseases eventually. The sensitivity and specificity of mNGS were compared to traditional pathogen detection methods.
Organism human metagenome
Data Type -
Data Accessibility Open-access
BioProject PRJCA008385
Release Date 2022-04-25
Submitter Ye Zhang (zhangye@hugobiotech.com)
Organization Hugobiotech Beijing Co.,Ltd.
Submission Date 2022-02-25
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX974-04-01 mNGS_Reads_1 158 Genome-Wide Association Study (GWAS) 27.0 MB zip 0

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