Os01g0578000
The rice Os01g0578000 was reported as RAD51C in 2012 [1] by researchers from China.
Contents
Annotated Information
Figure 2. Phenotypes of RAD51C-KO plants.[1].
Gene Symbol
- Os01g0578000 <=> OsRAD51C,RAD51C
Function
- RAD51C is essential for reproductive development by regulating meiosis as well as for DNA damage repair in somatic cells.
Phenotypic analysis
- Transferring RAD51C to the RAD51C-KO line restored fertility. Cytological analyses showed that the sterility of RAD51C-KO plants was associated with abnormal early meiotic processes in both megasporocytes and pollen mother cells (PMCs).
- PMCs had an absence of normal pachytene chromosomes and had abnormal chromosome fragments.
- The RAD51C-KO line showed no obvious difference from wild-type plants in mitosis in the anther wall cells, which was consistent with the observation that the RAD51C-KO line did not have obviously abnormal morphology during vegetative development.
- However, the RAD51C-KO line was sensitive to different DNA-damaging agents.
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Labs working on this gene
- National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Huazhong Agricultural
