Os01g0917400

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The rice Os01g0917400 was reported as OsC3H12 in 2012 [1] by researchers from China.

Annotated Information

Gene Symbol

  • Os01g0917400 <=> OsC3H12

Function

  • Genes in the CCCH family encode zinc finger proteins containing the motif with three cysteines and one histidine residues. [1] [2]
  • CCCH-type zinc finger proteins have essential functions in various developmental processes in plants.
  • CCCH family genes have been known to play important roles in RNA processing as RNA-binding proteins.
  • CCCH-type zinc finger proteins are RNA-binding proteins by virtue of the ability of their defining motif to directly bind to RNA, whereas most of the other zinc finger families are confirmed as DNA-binding or protein-binding proteins.

Expression

  • The expression profile indicated that most members of this subfamily are regulated by abiotic or biotic stresses, suggesting that they could have an effective role in stress tolerance.

Evolution

  • A typical CCCH protein usually contains 1–6 CCCH-type zinc finger motifs.
  • Based on the different numbers of amino acid spacers between cysteines and histidines in the CCCH motif, a consensus sequence for these was defined as C-X 4–15 -C-X 4–6 -C-X 3 -H (X represents any amino acid) based on the whole-genome analysis of rice and Arabidopsis CCCH proteins [1] [2]

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Labs working on this gene

  • State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, Shandong 271018, P.R. China

References

  1. ↑ 1.0 1.1 1.2 Wang D, Guo Y, Wu C, Yang G, Li Y, Zheng C. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics. 2008 Jan 27;9:44. doi: 10.1186/1471-2164-9-44. PubMed PMID: 18221561; PubMed Central PMCID: PMC2267713.
  2. ↑ 2.0 2.1 Peng X, Zhao Y, Cao J, Zhang W, Jiang H, Li X, Ma Q, Zhu S, Cheng B. CCCH-type zinc finger family in maize: genome-wide identification, classification and expression profiling under abscisic acid and drought treatments. PLoS One. 2012;7(7):e40120. doi: 10.1371/journal.pone.0040120. PubMed PMID: 22792223; PubMed Central PMCID: PMC3391233.

Structured Information