Os02g0215200
The rice Os02g0215200 was reported as OsHDAC2 in 2002 [1] by researchers from Korea.
Contents
Annotated Information
Gene Symbol
- Os02g0215200 <=> OsHDAC2, HDAC2, HDA710
Function
- Histone deacetylases (HDACs) modulate chromatin structure and transcription.
- HDACs have been studied as negative regulators in eukaryotic transcription.
- The OsHDAC1 gene encoded a protein of approximately 57 kDa that shared 73.5%, 72.7%, 79.9%, and 57.1% amino acid sequence identity with the OsHDAC2, OsHDAC3, maize RPD3, and human HDAC1 proteins, respectively.
- OsHDAC1 functions in the genome-wide programming of gene expression.
Expression
- OsHDAC1 was expressed at similar levels in the leaves, roots, and callus cells, whereas OsHDAC2 and OsHDAC3 were expressed in the roots and callus cells, but not in the leaves, exhibiting distinct tissue specificity.
Evolution
- Genomic structures and Southern blot analyses revealed that OsHDAC1, OsHDAC2, OsHDAC3 contained seven, six, and seven exons, respectively, and constituted a class I-type family in the rice genome.
Labs working on this gene
- Department of Biological Science, Myongji University, Yongin 449-728, Korea, and
- Department of Bioscience and Biotechnology, Sejong University, Seoul 143-747, Korea
References
- ↑ Jang IC, Pahk YM, Song SI, Kwon HJ, Nahm BH, Kim JK. Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture. Plant J. 2003 Feb;33(3):531-41. PubMed PMID: 12581311.
