Os02g0724000
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Contents
Annotated Information
Function
DTH2 behaves as a single Mendelian factor，it encodes a CONSTANS-like protein that promotes heading by inducing theflorigen genes Heading date 3a and RICE FLOWERING LOCUS T 1, and it acts independently of the known floral integrators Heading date 1 and Early heading date 1.DTH2 likely represents a target of human selection for adaptation to LD conditions during rice domestication and/or improvement, demonstrating an important role of minor-effect quantitative trait loci in crop adaptation and breeding.[1]
Expression
DTH2 transcripts were detected in all tissues examined,but its expression was most abundant in leaf blade and sheath,it is also found that DTH2 expression is controlled by the circadian clock [1]
Evolution
Research indicates that A4 allele of DHT2 may have undergone intensive selection during the northward expansion ofjaponicarice to NLD conditions in Asia.Another assay finds that the diversity at the genes surrounding DTH2 in japonica is reduced.It can be explained by the combination of domestication bottleneck and selective sweep around DTH2, providing additional evidence that DTH2 has been subjected to artificial selection during domestication or improvement ofjaponica rice.[1]
Labs working on this gene
[1]National Key Laboratory for Crop Genetics and Germplasm Enhancement, Jiangsu Plant Gene Engineering Research Center, Nanjing Agricultural University,Nanjing 210095, China
[2]National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China
[3]State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences,Beijing 100093, China
References
- ↑ 1.0 1.1 1.2 Wu W, Zheng XM, Lu G, Zhong Z, Gao H, Chen L, Wu C, Wang HJ, Wang Q, Zhou K,Wang JL, Wu F, Zhang X, Guo X, Cheng Z, Lei C, Lin Q, Jiang L, Wang H, Ge S, Wan J. Association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2775-80. doi: 10.1073/pnas.1213962110. Epub 2013 Feb 6. PubMed PMID:23388640; PubMed Central PMCID: PMC3581972.
