Os02g0817800

The rice Os02g0817800 was reported as rtbp1 in 2007 by researchers from the Korea.

Annotated Information

Gene Symbol

• Os02g0817800 <=> rtbp1

Function

• RTBP1 plays dual roles in rice (Oryza sativa), as both a negative regulator of telomere length and one of positive and functional components for proper architecture of telomeres.

Mutant

• rtbp1 plants displayed progressive and severe developmental abnormalities in both germination and postgermination growth of vegetative organs over four generations (G1 to G4). Reproductive organ formation, including panicles, stamens, and spikelets, was also gradually and severely impaired in G1 to G4 mutants. Up to 11.4, 17.2, and 26.7% of anaphases in G2, G3, and G4 mutant pollen mother cells, respectively, exhibited one or more chromosomal fusions, and this progressively increasing aberrant morphology was correlated with an increased frequency of anaphase bridges containing telomeric repeat DNA. Furthermore, 35S:anti-RTBP1 plants expressing lower levels of RTBP1 mRNA exhibited developmental phenotypes intermediate between the wild type and mutants in all aspects examined, including telomere length, vegetative and reproductive growth, and degree of genomic anomaly.

Labs working on this gene

• Department of Biology, College of Science, Yonsei University, Seoul 120-749, Korea
• School of Bioscience and Biotechnology, Chungnam National University, Daejeon 305-764, Korea
• National Research Laboratory of Plant Functional Genomics, Department of Life Science,Pohang University of Science and Technology, Pohang 790-784, Korea.