Os06g0613400

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The rice Os06g0613400 was reported as OsCOM1 in 2012 [1] by researchers from China.

Annotated Information

Gene Symbol

  • Os06g0613400 <=> OsCOM1,COM1

Function

  • COM1/SAE2 is a highly conserved gene from yeast to higher eukaryotes. Its orthologs, known to cooperate with the MRX complex (Mre11/Rad50/Xrs2), are required for meiotic DNA double-strand break (DSB) ends resection and specific mitotic DSB repair events.
  • OsCOM1 plays an important role in promoting homologous synapsis and recombination in rice meiosis.

Phenotypic analysis

  • The mutant plants showed normal vegetative growth and development, and could not be distinguished from the wild-type plant, but were completely sterile. The male gamete fertility was examined by staining with 1% I 2 -KI solution.
  • Almost all pollen grains in the mutant plant were shrunken, with an irregular appearance, and could not be stained, compared with those from the wild type .
  • Furthermore, the mutant flowers did not set seeds when pollinated with the wild-type pollens, demonstrating that the mutation prevented both male and female fertility.

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Labs working on this gene

  • State Key Laboratory of Plant Genomics and Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China

References

  1. ↑ Ji J, Tang D, Wang K, Wang M, Che L, Li M, Cheng Z. The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis. Plant J. 2012 Oct;72(1):18-30. doi: 10.1111/j.1365-313X.2012.05025.x. Epub 2012 Aug 1. PubMed PMID: 22507309.

Structured Information