Os06g0613400
The rice Os06g0613400 was reported as OsCOM1 in 2012 [1] by researchers from China.
Contents
Annotated Information
Gene Symbol
- Os06g0613400 <=> OsCOM1,COM1
Function
- COM1/SAE2 is a highly conserved gene from yeast to higher eukaryotes. Its orthologs, known to cooperate with the MRX complex (Mre11/Rad50/Xrs2), are required for meiotic DNA double-strand break (DSB) ends resection and specific mitotic DSB repair events.
- OsCOM1 plays an important role in promoting homologous synapsis and recombination in rice meiosis.
Phenotypic analysis
- The mutant plants showed normal vegetative growth and development, and could not be distinguished from the wild-type plant, but were completely sterile. The male gamete fertility was examined by staining with 1% I 2 -KI solution.
- Almost all pollen grains in the mutant plant were shrunken, with an irregular appearance, and could not be stained, compared with those from the wild type .
- Furthermore, the mutant flowers did not set seeds when pollinated with the wild-type pollens, demonstrating that the mutation prevented both male and female fertility.
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Labs working on this gene
- State Key Laboratory of Plant Genomics and Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
References
- ↑ Ji J, Tang D, Wang K, Wang M, Che L, Li M, Cheng Z. The role of OsCOM1 in homologous chromosome synapsis and recombination in rice meiosis. Plant J. 2012 Oct;72(1):18-30. doi: 10.1111/j.1365-313X.2012.05025.x. Epub 2012 Aug 1. PubMed PMID: 22507309.