Os07g0497100
The rice Os07g0497100 was reported as chr729 in 2012 [1] by researchers from France.
Contents
Annotated Information
Figure 1. The effects of the chr729 mutation on rice plant morphology.[1].
Gene Symbol
- Os07g0497100 <=> OsCHR729,chr729
Function
- The rice CHD3 protein CHR729 was required for many aspects of plant development.
- CHR729 can interact with dimethylated histone H3 lysine 4 (H3K4me2, a mark associated with moderately expressed or repressed genes) and with trimethylated histone H3 lysine 27 (H3K27me3, a mark associated with repressed genes), respectively, through the chromodomains and the plant homeodomain (PHD) finger of the protein.
- The rice CHD3 protein is a bifunctional chromatin regulator able to recognize and modulate H3K4 and H3K27 methylation over repressed or tissue specific genes, which may be associated with regulation of a gene transcription program of plant development.
- Loss of CHR729 Affected Many Aspects of Plant Development.
Phenotypic analysis
- The chr729 T-DNA mutation caused a set of morphological and growth defects, including short and narrow leaves, reduced stem elongation, reduced chlorophyll contents, and no secondary panicle branches (Fig. 1 ).
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Labs working on this gene
- National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 430070 Wuhan, China; and b Institut de Biologie des Plantes, Unité Mixte de Recherche 8618, Université Paris sud, 91405 Orsay, France
References
- ↑ 1.0 1.1 Hu Y, Liu D, Zhong X, Zhang C, Zhang Q, Zhou DX. CHD3 protein recognizes and regulates methylated histone H3 lysines 4 and 27 over a subset of targets in the rice genome. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5773-8. doi: 10.1073/pnas.1203148109. Epub 2012 Mar 26. PubMed PMID: 22451926; PubMed Central PMCID: PMC3326492.
