Os07g0580500

The rice Os07g0580500 was reported as OsBZR1 in 2007 by researchers from the China.

Annotated Information

Gene Symbol

• Os07g0580500 <=> OsBZR1

Function

• A conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice.

Mutant

• Suppressing OsBZR1 expression by RNAi resulted in dwarfism, erect leaves, reduced BR sensitivity, and altered BR-responsive gene expression in transgenic rice plants, demonstrating an essential role of OsBZR1 in BR responses in rice.
• Mutation of a putative 14-3-3-binding site of OsBZR1 abolished its interaction with the 14-3-3 proteins in yeast and in vivo. Such mutant OsBZR1 proteins suppressed the phenotypes of the Arabidopsis bri1–5 mutant and showed an increased nuclear distribution compared with the wild-type protein, suggesting that 14-3-3proteins directly inhibit OsBZR1 function at least in part by reducing its nuclear localization.

Labs working on this gene

• Key Laboratory of Photosynthesis and Environmental Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China;
• Department of Plant Biology, Carnegie Institution, Stanford, CA 94305; and ‡Department of Plant Pathology, Plant Molecular;
• Cellular Biology Program, University of Florida, Gainesville, FL 32611