Os11g0704500

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The rice Os11g0592200 was reported as OsMT1a in 2009 [1] by researchers from China.

Annotated Information

Figure 1 (Snapshot). Responses to drought of the OsMT1a-transgenic rice and wild type.[1].

Gene Symbol

  • Os11g0704500 <=> OsMT1a,MT1a,MTa

Function

  • Metallothioneins (MTs) are small, cysteine-rich, metal-binding proteins that may be involved in metal homeostasis and detoxification in both plants and animals.
  • OsMT1a, encodes a type 1 metallothionein.

Phenotypic analysis

  • Both transgenic plants and yeasts harboring OsMT1a accumulated more Zn(2+) than wild type controls, suggesting OsMT1a is most likely to be involved in zinc homeostasis.
  • Transgenic rice plants overexpressing OsMT1a demonstrated enhanced tolerance to drought.
  • The examination of antioxidant enzyme activities demonstrated that catalase (CAT), peroxidase (POD) and ascorbate peroxidase (APX) were significantly elevated in transgenic plants. Furthermore, the transcripts of several Zn(2+)-induced CCCH zinc finger transcription factors accumulated in OsMT1a transgenic plants, suggesting that OsMT1a not only participates directly in ROS scavenging pathway but also regulates expression of the zinc finger transcription factors via the alteration of Zn(2+) homeostasis, which leads to improved plant stress tolerance.

Expression

  • Expression analysis revealed that OsMT1a predominantly expressed in the roots, and was induced by dehydration.
  • The OsMT1a expression was also induced specifically by Zn treatment.

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Labs working on this gene

  • State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, 100101 Beijing, China

References

  1. 1.0 1.1 Yang Z, Wu Y, Li Y, Ling HQ, Chu C. OsMT1a, a type 1 metallothionein, plays the pivotal role in zinc homeostasis and drought tolerance in rice. Plant Mol Biol. 2009 May;70(1-2):219-29. doi: 10.1007/s11103-009-9466-1. PubMed PMID: 19229638.

Structured Information