Os12g0631100

The rice gene Os12g0631100 was reported as OsRab5B2 in 2010 by researchers from China.

Annotated Information

Gene Symbol

• Os12g0631100 <=> glup4(esp8), esp8, glup4, OsRab5B2, Rab5a, OsRab5a, gpa1, GPA1/Rab5a

Function

• The gene corresponding to the gpa1 mutation was found to be OsRab5a, which encodes a small GTPase.
• OsRab5a plays an essential role in trafficking of storage protein to PBII, possibly as part of its function in organizing the endomembrane system in developing endosperm cells of rice.

Mutation

• gpa1 mutant accumulates 57 kDa pro-glutelins in seeds and whose endosperm has a floury appearance.
• Transmission electron microscopy analysis showed that the gpa1 endosperm cells have an enlarged ER lumen and a smaller protein body II (PBII), and accumulated three types of newly generated subcellular structures. Moreover, a proportion of glutelins in the gpa1 endosperm cells were not delivered to PBII, and instead were mis-targeted to two of the newly generated structures or secreted.

Expression

• OsRab5a is widely expressed in rice plants. Quantitative RT-PCR analysis showed that the highest expression of OsRab5a occurs in roots.

Evolution

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Labs working on this gene

• State Key Laboratory for Crop Genetics and Germplasm Enhancement, Jiangsu Plant Gene Engineering Research Center, Nanjing Agricultural University, Nanjing 210095, China,
• National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China,
• College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China