Difference between revisions of "Os05g0196500"
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===Function=== | ===Function=== | ||
| − | This gene encodes a histone H3K4 demethylase —JMJ703 which involves in both transposon(TE) silencing and stem elongation in rice. JMJ703 is a JmjC domain-containing protein, which can specifically demethylate methylated histone H3 lysine 4 and reverse all three forms of H3K4me(mono-, di-, or trimethylation). It is required for TEs silencing. Impaired JMJ703 activity leads to elevated levels of H3K4me3, the misregulation of numerous endogenous genes, and the transpositional reactivation of two families of non-LTR retrotransposons. However, loss of JMJ703 does not affect TEs (such as Tos17) previously found to be silenced by other epigenetic pathways, indicating that different subsets of TEs may be regulated by distinct epigenetic pathways. Besides, loss-of-function mutation of the gene reduces cell division rate of the stem and size of plant stature, showing the importance of this protein in plant growth. | + | This gene encodes a histone H3K4 demethylase —JMJ703 which involves in both transposon(TE) silencing and stem elongation in rice. JMJ703 is a JmjC domain-containing protein, which can specifically demethylate methylated histone H3 lysine 4 and reverse all three forms of H3K4me(mono-, di-, or trimethylation). It is required for TEs silencing. Impaired JMJ703 activity leads to elevated levels of H3K4me3, the misregulation of numerous endogenous genes, and the transpositional reactivation of two families of non-LTR retrotransposons. However, loss of JMJ703 does not affect TEs (such as Tos17) previously found to be silenced by other epigenetic pathways, indicating that different subsets of TEs may be regulated by distinct epigenetic pathways. ''jmj703'' mutants displayed pleiotropic phenotypes (erect leaves, significantly decreased secondary panicle branches and abnormal phenotypes of grains), the most obvious of which was dwarfism. Besides, loss-of-function mutation of the gene reduces cell division rate of the stem and size of plant stature, showing the importance of this protein in plant growth. |
===Expression=== | ===Expression=== | ||
Revision as of 10:38, 14 May 2014
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Contents
Annotated Information
Function
This gene encodes a histone H3K4 demethylase —JMJ703 which involves in both transposon(TE) silencing and stem elongation in rice. JMJ703 is a JmjC domain-containing protein, which can specifically demethylate methylated histone H3 lysine 4 and reverse all three forms of H3K4me(mono-, di-, or trimethylation). It is required for TEs silencing. Impaired JMJ703 activity leads to elevated levels of H3K4me3, the misregulation of numerous endogenous genes, and the transpositional reactivation of two families of non-LTR retrotransposons. However, loss of JMJ703 does not affect TEs (such as Tos17) previously found to be silenced by other epigenetic pathways, indicating that different subsets of TEs may be regulated by distinct epigenetic pathways. jmj703 mutants displayed pleiotropic phenotypes (erect leaves, significantly decreased secondary panicle branches and abnormal phenotypes of grains), the most obvious of which was dwarfism. Besides, loss-of-function mutation of the gene reduces cell division rate of the stem and size of plant stature, showing the importance of this protein in plant growth.
Expression
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Evolution
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Labs working on this gene
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References
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Structured Information
| Gene Name |
Os05g0196500 |
|---|---|
| Description |
Transcription factor jumonji, JmjN domain containing protein |
| Version |
NM_001061402.1 GI:115462534 GeneID:4338043 |
| Length |
6692 bp |
| Definition |
Oryza sativa Japonica Group Os05g0196500, complete gene. |
| Source |
Oryza sativa Japonica Group ORGANISM Oryza sativa Japonica Group
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
clade; Ehrhartoideae; Oryzeae; Oryza.
|
| Chromosome | |
| Location |
Chromosome 5:5922219..5928910 |
| Sequence Coding Region |
5922819..5923145,5923247..5923327,5923412..5923489,5923595..5924062,5924414..5924638 |
| Expression | |
| Genome Context |
<gbrowseImage1> name=NC_008398:5922219..5928910 source=RiceChromosome05 preset=GeneLocation </gbrowseImage1> |
| Gene Structure |
<gbrowseImage2> name=NC_008398:5922219..5928910 source=RiceChromosome05 preset=GeneLocation </gbrowseImage2> |
| Coding Sequence |
<cdnaseq>atgatgggggttaccaccacgctcaacgaggacactgaaccctctattccacctggatttggaccttttgctacccttccgttatggggaatccacaatgatgccaaacctgctgttactcattctactcctgttcaagcattgcaaagcattagaaaagacagcgaagaatgccaacccagtgcggctgtgtctcggagtgatacaccttgcagcacttccggaacccagacatgcagaaaatcactgcgtaacagacccccaatagactatagccgctttgaacatatatcggatgaagattctgatgtcgaaatagtggaaaaggatgtaagttcaacgagacgcagacaacagctaccgaaaggagtacttcgaggatgtgcagaatgcagtgactgtcaaaaggttatcgcaaaatggaatccagctggtgcacgcaggcctgttcttgatgaggctcctgttttctatccaacagaggaggaatttgaagacactctaaaatacattgagagtatacggccaatggcggaaccatatggtatttgccgtattgtcccaccatcttcttggaagcctccatgccttcttaaagataaaagcatatgggaaggatcaaaattctctactcgggtacaaaaggttgacaagctccaaaaccgtaaatcatcaaaaaagggcagaagaggtggaatgatgaagaggagaaagcttgcagagtcagaggagaacagtgccactgctcacactcagacagggatgcagcaaagtccagagagatttggatttgaacctgggccagagttcacgttacagacatttcagaaatatgcagatgatttcagtaagcagtactttaggaaagatacatcgatggattcagtaccatcagtggaagatattgaaggtgagtactggcgcatcgttgaggttcccacagaagagatagaggtgatatatggtgctgatctggagactggaactttcggcagtggttttccaaaattatctcctgagacaaaatctgatgctgaggataaatatgcacaatctggttggaatctaaataacttgcctagactacaaggttcagttctttctttcgagggcggtgacatttctggtgttctagtgccttgggtgtatgttggcatgtgtttttcatcattctgctggcatgttgaagaccatcatttatactcactaaactacatgcattggggtgccccaaagttgtggtatggagttccaggaaaggatgctgtgaatttggaatctgcaatgaggaaacatctacctgaattatttgaggagcaacctgatttgctacacaaccttgttacccagttttcaccatcgctgctgaaatctgaaggagtacatgtataccgttgtgttcagcatgagggcgagtttgtcttgacattcccaagggcgtaccatgctggtttcaattgtggcttcaattgtgccgaagctgttaatgtggctcctattgattggttaccgattggacataatgctgtagagctttatcgtgagcaagctaggaaaataaccatttctcatgataagttgttgttgggggctgcaagagaagcaataagagctcagtgggatatcctattcctcaagaggaatactgctgataatatgaggtggaagagtatatgcggagctgatagcactatattcaaggctcttaaggcacgaattgagacagagttggtgcaaaggaaaactctaggtgttccagctcaatcaaggaaaatggatgctgaattcgattccattgatagggaatgtgccttgtgctactatgatttacatctttctgcttctggctgtccatgctgcccagagaaatatgcttgccttgtacatgcaaagcaactttgctcatgtgactgggacaaaaggtttttcctattccgctatgatgtcaatgagctaaatatcttagctgatgctttaggggggaaattaagtgccattcatagatggggcgtctctgatcttggattaagtttgagttcatgtgtcaaacgagaaaaggtccaagattccaagactgttcgcagattaactgatggtccaagaaggtcttacatgtcacaggcatcagcagtatccttggtttcttcttctacttccaatgaacagaaagatgaaggaaataagatcatgaagatagctagcccacagacaaataatgtgtgcccttctgtcgagcaaaggaaatcagagaatatttcaccattgaaggagccatgtgtaaggaatgagttgtcatgtacaacaaattctgatagtaacggattgcaatataatggaggacttggaggccataaaggatctgcaccaggcttgccagtttcttctagcccatcattttcttccaacgttgcaacaaggcccattagtacttcaagtgtatccatgaaaattgtgcaaggcttggtggcatctaaaagttgtatacaagcttcctctcgaactggagacagtagatcattgcttggtgagcatcataacagatcaccggcaatgattcatgatggaaccaacatgaagtccagtttggaaagctcaaacaattcttgcaggttgattgcatctgactataatgcaactccgtgtcattcatccaaggatcaggtattagtaacaccagggactaatgcctcagtagtgactctgaaagatagcagccaggtccatagtgcgtcaagtcagcagtttgtcagaactggcccatggacacaaagtgcttctcatgaagcatcatcacctagtacctctgctttgaagccttctttagatccccctgccatgaaaaatctgtatgggggttttactcaaggcagtgcccatcctggacctccaagtttcagtaatcagcaaccaaatgatgggcgtcttcaaagaacatctgaatctctaccaggtgtggaagctagagctaggggacatccaactgtcacggcacagcctgcactagaaattcacagcaggaatggaggtgcacagaagggtcctcgcatagccaatgttgtgcatcgtttcaagtgctctgttgaacctctcgaaattggtgttgtgctatcagggaggctgtggtcttcaagccaagcaatcttcccgaaagggtttagaagcagagtgaaatacttcagcattgtggatccaatccaaatggcatactacatatcggaaatactggatgctgggatgcaggggcctctgtttatggtaaaattagagaactgtccaggtgaagttttcattaacttatctccaaccaagtgttggaacatggtccgtgaaaggctgaacatggaaataaggaggcaacttaatatgggaaaatcaaatcttcctacattgcagcctccaggatcagttgatggtcttgaaatgtttggtttattatcaccaccaatagttcaggcaatttgggcgcgggacagagatcacatctgtacagagtactggagatcaaggccccatgttctcattgaggatccaaacaatcggcatatgttatctcagggtccacctctccttgccctgaggggtctcatccaaagggctaaccgggatgaattgcaagtcctgcggagtttgatgacgaacagcaacaatttggatgatagctccaggcaacaggccgcgcacattatcgaagaggagattgcgaagcaattgtgctga</cdnaseq> |
| Protein Sequence |
<aaseq>MMGVTTTLNEDTEPSIPPGFGPFATLPLWGIHNDAKPAVTHSTP VQALQSIRKDSEECQPSAAVSRSDTPCSTSGTQTCRKSLRNRPPIDYSRFEHISDEDS DVEIVEKDVSSTRRRQQLPKGVLRGCAECSDCQKVIAKWNPAGARRPVLDEAPVFYPT EEEFEDTLKYIESIRPMAEPYGICRIVPPSSWKPPCLLKDKSIWEGSKFSTRVQKVDK LQNRKSSKKGRRGGMMKRRKLAESEENSATAHTQTGMQQSPERFGFEPGPEFTLQTFQ KYADDFSKQYFRKDTSMDSVPSVEDIEGEYWRIVEVPTEEIEVIYGADLETGTFGSGF PKLSPETKSDAEDKYAQSGWNLNNLPRLQGSVLSFEGGDISGVLVPWVYVGMCFSSFC WHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNLESAMRKHLPELFEEQPDLLHNLVTQ FSPSLLKSEGVHVYRCVQHEGEFVLTFPRAYHAGFNCGFNCAEAVNVAPIDWLPIGHN AVELYREQARKITISHDKLLLGAAREAIRAQWDILFLKRNTADNMRWKSICGADSTIF KALKARIETELVQRKTLGVPAQSRKMDAEFDSIDRECALCYYDLHLSASGCPCCPEKY ACLVHAKQLCSCDWDKRFFLFRYDVNELNILADALGGKLSAIHRWGVSDLGLSLSSCV KREKVQDSKTVRRLTDGPRRSYMSQASAVSLVSSSTSNEQKDEGNKIMKIASPQTNNV CPSVEQRKSENISPLKEPCVRNELSCTTNSDSNGLQYNGGLGGHKGSAPGLPVSSSPS FSSNVATRPISTSSVSMKIVQGLVASKSCIQASSRTGDSRSLLGEHHNRSPAMIHDGT NMKSSLESSNNSCRLIASDYNATPCHSSKDQVLVTPGTNASVVTLKDSSQVHSASSQQ FVRTGPWTQSASHEASSPSTSALKPSLDPPAMKNLYGGFTQGSAHPGPPSFSNQQPND GRLQRTSESLPGVEARARGHPTVTAQPALEIHSRNGGAQKGPRIANVVHRFKCSVEPL EIGVVLSGRLWSSSQAIFPKGFRSRVKYFSIVDPIQMAYYISEILDAGMQGPLFMVKL ENCPGEVFINLSPTKCWNMVRERLNMEIRRQLNMGKSNLPTLQPPGSVDGLEMFGLLS PPIVQAIWARDRDHICTEYWRSRPHVLIEDPNNRHMLSQGPPLLALRGLIQRANRDEL QVLRSLMTNSNNLDDSSRQQAAHIIEEEIAKQLC</aaseq> |
| Gene Sequence |
<dnaseqindica>601..927#1029..1109#1194..1271#1377..1844#2196..2420#2545..2706#3256..3624#3704..5144#5352..5455#5534..5731#6029..6292#gtgcctgtgcttgtgcccaacaagaggagagcaaaatttcccctcgtcgtcagctcgctcgcctgcgccaccgccgaccccccatccatccctccccggcgacggcgaccggagcagaggggggttaggctcgccgccgccgccgccgccgccgcttctgctgcttctcccgccgccccgcatcgcatctatcccggtgagcatcccctacccacgcgctttttgccacgaatttgtagttgtagagagacctggaactggaagccctttttcctcttaatttgcccttaaccttgataatactaatagcaaaaaataataaaatagtaaaaaaaaattggggggttgaactgagctgaaccccccatgtctcatgtttagatctgtgcccctgatgtgcctgcctgctttggaacgatttcgttgtgagttgattccaatggtagatccatttcttcaagatgtgttgtgattttttttctcaaggttgtggatcaggatcatggcctaagccgtgaaatgcaatgaacttgacagattgaaccataagcaaaatttgttagctatcatggtgaaactaatttttcttctgatgcagtaatgatgggggttaccaccacgctcaacgaggacactgaaccctctattccacctggatttggaccttttgctacccttccgttatggggaatccacaatgatgccaaacctgctgttactcattctactcctgttcaagcattgcaaagcattagaaaagacagcgaagaatgccaacccagtgcggctgtgtctcggagtgatacaccttgcagcacttccggaacccagacatgcagaaaatcactgcgtaacagacccccaatagactatagccgctttgaacatatatcggatgaagattctgatgtcgaaatagtggaaaaggttggtactcatgaaagccgccactcttttgtcaacatttacctgacatttatacatgatgttaatgcttgccatggtattgctctattctttggacacaggatgtaagttcaacgagacgcagacaacagctaccgaaaggagtacttcgaggatgtgcagaatgcagtgactgtcaaaaggtttcaaatctattgccaaattgctatgctacttccttgatgatactgttgccttgcttgcttatttgactacatattattcaggttatcgcaaaatggaatccagctggtgcacgcaggcctgttcttgatgaggctcctgttttctatccaacagaggaggtacctttccccttgctaactgttgtactgtattgtatttagtactgtgatctttctgtatttatcgtcatatccccagatttgtgatattgtctcatggatcaggaatttgaagacactctaaaatacattgagagtatacggccaatggcggaaccatatggtatttgccgtattgtcccaccatcttcttggaagcctccatgccttcttaaagataaaagcatatgggaaggatcaaaattctctactcgggtacaaaaggttgacaagctccaaaaccgtaaatcatcaaaaaagggcagaagaggtggaatgatgaagaggagaaagcttgcagagtcagaggagaacagtgccactgctcacactcagacagggatgcagcaaagtccagagagatttggatttgaacctgggccagagttcacgttacagacatttcagaaatatgcagatgatttcagtaagcagtactttaggaaagatacatcgatggattcagtaccatcagtggaagatattgaaggtgagtactggcgcatcgttgaggttcccacagaagagatagaggtactgagcttctgttgactctcaacaaattatactgacgtgcttgcaatttatacctcagttgaactttgaaaattttatcaattcctaatttttggatatgtggtctctggtctcggattatggccctgctggagagtttctaaataagttatggattgccttgctgtatatgctatcatgacctccaaaaattagtgctacttttacatagccatatcatttgtagatgagacattttaggcctaactgtattgctgtaactgcataaatgttgtatcatgtaggatagtttccgtacaactactgttgtttttccgtacttatcagaagatgtgatatattatgtaggtgatatatggtgctgatctggagactggaactttcggcagtggttttccaaaattatctcctgagacaaaatctgatgctgaggataaatatgcacaatctggttggaatctaaataacttgcctagactacaaggttcagttctttctttcgagggcggtgacatttctggtgttctagtgccttgggtgtatgttggcatgtgtttttcatcattctgctgggtaagatgcttgtgatattgcttgtcatgactttctgttctagttgtgcttcttgattcttttttttcccgaaactatccaacctgagatttgttacactcaattgtgttatgtctactaacagcatgttgaagaccatcatttatactcactaaactacatgcattggggtgccccaaagttgtggtatggagttccaggaaaggatgctgtgaatttggaatctgcaatgaggaaacatctacctgaattatttgaggagcaacctgatttgctacacaaccttgtgagtatcttgattggcagttttctgtttgtgcccaggaaggaagccttttgtatctagtaacaactaatgctcgatagactctgtgatagcagtgaatactgggagctacttataatcatgccacatgaaatgcatttttggaagttataagaaatagataattttctaaccttctgtacaaaagaaggtatatttttgtaacatcattttcctactgcattattgttatggtagtatgccagcaaccaataacttttcaattctctctattttccaatcactactaaatcatctaactttagacatctttataacgcaagactcagcaagagctcaccatgtgtaaaacagcaccaacacattaactattcatgtggtagtaaagaaatggtttgtctgagtgtctaaagcattatgttctattctttgaatttagacataagatttttaaaaaaaatgatgtgagcacttatatatgggttgtgtttgctatgatgtgtatgagcagcatttttatgtgttttgttatgacaacctctaccgcaggttacccagttttcaccatcgctgctgaaatctgaaggagtacatgtataccgttgtgttcagcatgagggcgagtttgtcttgacattcccaagggcgtaccatgctggtttcaattgtggcttcaattgtgccgaagctgttaatgtggctcctattgattggttaccgattggacataatgctgtagagctttatcgtgagcaagctaggaaaataaccatttctcatgataagttgttgttgggggctgcaagagaagcaataagagctcagtgggatatcctattcctcaagaggaatactgctgataatatgaggtggaagagtatatgcggagctgatagcactatattcaaggctcttaaggtaaagtccaattaaaatatgtgttgtattgtttgtttaagaactcaatggaagctcatacttaaaattctctgtttaggcacgaattgagacagagttggtgcaaaggaaaactctaggtgttccagctcaatcaaggaaaatggatgctgaattcgattccattgatagggaatgtgccttgtgctactatgatttacatctttctgcttctggctgtccatgctgcccagagaaatatgcttgccttgtacatgcaaagcaactttgctcatgtgactgggacaaaaggtttttcctattccgctatgatgtcaatgagctaaatatcttagctgatgctttaggggggaaattaagtgccattcatagatggggcgtctctgatcttggattaagtttgagttcatgtgtcaaacgagaaaaggtccaagattccaagactgttcgcagattaactgatggtccaagaaggtcttacatgtcacaggcatcagcagtatccttggtttcttcttctacttccaatgaacagaaagatgaaggaaataagatcatgaagatagctagcccacagacaaataatgtgtgcccttctgtcgagcaaaggaaatcagagaatatttcaccattgaaggagccatgtgtaaggaatgagttgtcatgtacaacaaattctgatagtaacggattgcaatataatggaggacttggaggccataaaggatctgcaccaggcttgccagtttcttctagcccatcattttcttccaacgttgcaacaaggcccattagtacttcaagtgtatccatgaaaattgtgcaaggcttggtggcatctaaaagttgtatacaagcttcctctcgaactggagacagtagatcattgcttggtgagcatcataacagatcaccggcaatgattcatgatggaaccaacatgaagtccagtttggaaagctcaaacaattcttgcaggttgattgcatctgactataatgcaactccgtgtcattcatccaaggatcaggtattagtaacaccagggactaatgcctcagtagtgactctgaaagatagcagccaggtccatagtgcgtcaagtcagcagtttgtcagaactggcccatggacacaaagtgcttctcatgaagcatcatcacctagtacctctgctttgaagccttctttagatccccctgccatgaaaaatctgtatgggggttttactcaaggcagtgcccatcctggacctccaagtttcagtaatcagcaaccaaatgatgggcgtcttcaaagaacatctgaatctctaccaggtgtggaagctagagctaggggacatccaactgtcacggcacagcctgcactagaaattcacagcaggaatggaggtgcacagaagggtcctcgcatagccaatgttgtgcatcgtttcaagtgctctgttgaacctctcgaaattggtgttgtgctatcagggaggctgtggtcttcaagccaagcaatcttcccgaaaggtttgcattttgacagatcattggcagtacctcaataaatttagtgtttaggtcaaagaatttctgttatccgggagcttagtgttatgtctttgcatccatgaattttgctgtctttgatctatggtagttatactctatagtaattctgctgttgttttctgaatggctgtactcacaaatgttacactctctttgtaaatgcagggtttagaagcagagtgaaatacttcagcattgtggatccaatccaaatggcatactacatatcggaaatactggatgctgggatgcaggggcctctgtttatggtaaatttaagtttctcagctgtctttatgtatctgtcttagcatctgtacatattattgctcatttcatttttgcaggtaaaattagagaactgtccaggtgaagttttcattaacttatctccaaccaagtgttggaacatggtccgtgaaaggctgaacatggaaataaggaggcaacttaatatgggaaaatcaaatcttcctacattgcagcctccaggatcagttgatggtcttgaaatgtttggtttattatcaccaccaatagttcaggtgagacattaatgtctggtatcctcatgattgatctctaaggcctgtattggcattgcgaggccctttttataatagtgatttatgcacttataagtgaaaggaaatatatattagtatttcgaagtatttcatctcttttaagattccttaagatggcatgaatgactggagtaactagccctgctgcaggcttacatgctaagcttgttaattaagcatgtagttgattacctgtagctttggtctgtcaagttgatttgttggagccaatctttgacactgcaacttaaacaggcaatttgggcgcgggacagagatcacatctgtacagagtactggagatcaaggccccatgttctcattgaggatccaaacaatcggcatatgttatctcagggtccacctctccttgccctgaggggtctcatccaaagggctaaccgggatgaattgcaagtcctgcggagtttgatgacgaacagcaacaatttggatgatagctccaggcaacaggccgcgcacattatcgaagaggagattgcgaagcaattgtgctgagaagggtaaataccggctggctgttgtactttagatggcatgaatatttttttttccgacagggttaagcagatctaaaaccgaggcttgcttctccccttgcctttcatgcccattctttccattcttgagcccataccataagatttatgcttcaggtgactgttgtttcattgactgacttgtgtacatacagatgtgttgtgttcctaaatgctagccagctgcctcatctttcctgtaaaactcatgttgtgttcagctgtccagttaagtagggttgcttctagttcagagatctttggacagtcaaaatgtccatgccagatgtatctgctatgttattactttccagtctaacagtgattttgtgctgctgctagcaggcactcgagttttc</dnaseqindica> |
| External Link(s) |
