Difference between revisions of "Os05g0597100"
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===Evolution=== | ===Evolution=== | ||
* Overexpression of '''''HDT701''''' in transgenic rice leads to decreased levels of histone H4 acetylation and enhanced susceptibility to the rice pathogens M. oryzae and Xanthomonas oryzae pv oryzae (Xoo). | * Overexpression of '''''HDT701''''' in transgenic rice leads to decreased levels of histone H4 acetylation and enhanced susceptibility to the rice pathogens M. oryzae and Xanthomonas oryzae pv oryzae (Xoo). | ||
| − | * By contrast, silencing of HDT701 in transgenic rice causes elevated levels of histone H4 acetylation and elevated transcription of pattern recognition receptor (PRR) and defense-related genes, increased generation of reactive oxygen species after pathogen-associated molecular pattern elicitor treatment, as well as enhanced resistance to both M. oryzae and Xoo. | + | * By contrast, silencing of '''''HDT701''''' in transgenic rice causes elevated levels of histone H4 acetylation and elevated transcription of pattern recognition receptor (PRR) and defense-related genes, increased generation of reactive oxygen species after pathogen-associated molecular pattern elicitor treatment, as well as enhanced resistance to both M. oryzae and Xoo. |
==Labs working on this gene== | ==Labs working on this gene== | ||
Latest revision as of 04:07, 22 October 2016
The rice Os05g0597100 was reported as HDT701 in 2012 [1] by researchers from USA and China.
Contents
Annotated Information
Gene Symbol
- Os05g0597100 <=> HDT701,OsHDT1
Function
- HDT701 is a member of the plant-specific HD2 subfamily of HDACsencodes which a Histone H4 Deacetylase.
- HDT701 negatively regulates innate immunity by modulating the levels of histone H4 acetylation of PRR and defense-related genes in rice.
Expression
- Transcription of HDT701 is increased in the compatible reaction and decreased in the incompatible reaction after infection by the fungal pathogen Magnaporthe oryzae.
- HDT701 can bind to defense-related genes to regulate their expression.
Evolution
- Overexpression of HDT701 in transgenic rice leads to decreased levels of histone H4 acetylation and enhanced susceptibility to the rice pathogens M. oryzae and Xanthomonas oryzae pv oryzae (Xoo).
- By contrast, silencing of HDT701 in transgenic rice causes elevated levels of histone H4 acetylation and elevated transcription of pattern recognition receptor (PRR) and defense-related genes, increased generation of reactive oxygen species after pathogen-associated molecular pattern elicitor treatment, as well as enhanced resistance to both M. oryzae and Xoo.
Labs working on this gene
- Department of Plant Pathology, Ohio State University, Columbus, Ohio 43210
- State Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China
- Department of Plant and Soil Sciences, Delaware Biotechnology Institute, University of Delaware, Newark, Delaware 19711
References
- ↑ Ding B, Bellizzi Mdel R, Ning Y, Meyers BC, Wang GL. HDT701, a histone H4 deacetylase, negatively regulates plant innate immunity by modulating histone H4 acetylation of defense-related genes in rice. Plant Cell. 2012 Sep;24(9):3783-94. doi: 10.1105/tpc.112.101972. Epub 2012 Sep 11. PubMed PMID: 22968716; PubMed Central PMCID: PMC3480302.
