Difference between revisions of "Os01g0578000"
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| − | + | The rice '''''Os01g0578000''''' was reported as '''''RAD51C''''' in 2012 <ref name="ref1" /> by researchers from China. | |
==Annotated Information== | ==Annotated Information== | ||
| + | [[File:223-Os01g0578000.png|right|thumb|427px|'''Figure 2.''' ''Phenotypes of RAD51C-KO plants.<ref name="ref1" />.'']] | ||
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| + | ===Gene Symbol=== | ||
| + | *'''''Os01g0578000''''' '''''<=>''''' '''''OsRAD51C,RAD51C''''' | ||
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===Function=== | ===Function=== | ||
| − | + | *'''''RAD51C''''' is essential for reproductive development by regulating meiosis as well as for DNA damage repair in somatic cells. | |
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| − | === | + | ===Phenotypic analysis=== |
| − | + | * Transferring RAD51C to the RAD51C-KO line restored fertility. Cytological analyses showed that the sterility of RAD51C-KO plants was associated with abnormal early meiotic processes in both megasporocytes and pollen mother cells (PMCs). | |
| + | * PMCs had an absence of normal pachytene chromosomes and had abnormal chromosome fragments. | ||
| + | * The RAD51C-KO line showed no obvious difference from wild-type plants in mitosis in the anther wall cells, which was consistent with the observation that the RAD51C-KO line did not have obviously abnormal morphology during vegetative development. | ||
| + | * However, the RAD51C-KO line was sensitive to different DNA-damaging agents. | ||
You can also add sub-section(s) at will. | You can also add sub-section(s) at will. | ||
==Labs working on this gene== | ==Labs working on this gene== | ||
| − | + | * National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Huazhong Agricultural | |
==References== | ==References== | ||
| − | + | <references> | |
| − | + | * <ref name="ref1"> | |
| + | Kou Y, Chang Y, Li X, Xiao J, Wang S. The rice RAD51C gene is required for the | ||
| + | meiosis of both female and male gametocytes and the DNA repair of somatic cells. | ||
| + | J Exp Bot. 2012 Sep;63(14):5323-35. doi: 10.1093/jxb/ers190. PubMed PMID: | ||
| + | 22859673; PubMed Central PMCID: PMC3431001. | ||
| + | </ref> | ||
| + | </references> | ||
==Structured Information== | ==Structured Information== | ||
[[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 1]] | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 1]] | ||
Latest revision as of 13:53, 14 February 2017
The rice Os01g0578000 was reported as RAD51C in 2012 [1] by researchers from China.
Contents
Annotated Information
Figure 2. Phenotypes of RAD51C-KO plants.[1].
Gene Symbol
- Os01g0578000 <=> OsRAD51C,RAD51C
Function
- RAD51C is essential for reproductive development by regulating meiosis as well as for DNA damage repair in somatic cells.
Phenotypic analysis
- Transferring RAD51C to the RAD51C-KO line restored fertility. Cytological analyses showed that the sterility of RAD51C-KO plants was associated with abnormal early meiotic processes in both megasporocytes and pollen mother cells (PMCs).
- PMCs had an absence of normal pachytene chromosomes and had abnormal chromosome fragments.
- The RAD51C-KO line showed no obvious difference from wild-type plants in mitosis in the anther wall cells, which was consistent with the observation that the RAD51C-KO line did not have obviously abnormal morphology during vegetative development.
- However, the RAD51C-KO line was sensitive to different DNA-damaging agents.
You can also add sub-section(s) at will.
Labs working on this gene
- National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Huazhong Agricultural
