Difference between revisions of "Os12g0622500"
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| − | + | The rice '''Os12g0622500''' was reported as ''' OsSpo11-4''' in 2011 <ref name="ref1" /> by researchers from the China. | |
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==Annotated Information== | ==Annotated Information== | ||
| + | ===Gene Symbol=== | ||
| + | *'''Os12g0622500 <=> OsSpo11-4''' | ||
===Function=== | ===Function=== | ||
| − | + | *'''Spo11''' is essential for initiating meiotic recombination and this function appears conserved among other eukaryotes. | |
| − | + | ===Mutant=== | |
| − | === | + | *'''OsSpo11-4''' exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg2+ and independent of OsTopVIB, despite its interaction with OsTopVIB. We further analyzed the biological function of OsSpo11-4 by RNA interference and found that down-regulated expression of OsSpo11-4 led to defects in male meiosis, indicating '''OsSpo11-4''' is required for meiosis. |
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==Labs working on this gene== | ==Labs working on this gene== | ||
| − | + | *Chinese Ministry of Science and Technology | |
| + | *Natural Science Fundation of China | ||
==References== | ==References== | ||
| − | + | <references> | |
| + | <ref name="ref1"> | ||
| + | OsSpo11-4, a Rice Homologue of the Archaeal TopVIA Protein, Mediates Double-Strand DNA Cleavage and Interacts with OsTopVIB | ||
| + | </ref> | ||
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| + | </references> | ||
| + | <br> | ||
==Structured Information== | ==Structured Information== | ||
[[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 12]] | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 12]] | ||
Latest revision as of 01:01, 24 February 2017
The rice Os12g0622500 was reported as OsSpo11-4 in 2011 [1] by researchers from the China.
Contents
Annotated Information
Gene Symbol
- Os12g0622500 <=> OsSpo11-4
Function
- Spo11 is essential for initiating meiotic recombination and this function appears conserved among other eukaryotes.
Mutant
- OsSpo11-4 exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg2+ and independent of OsTopVIB, despite its interaction with OsTopVIB. We further analyzed the biological function of OsSpo11-4 by RNA interference and found that down-regulated expression of OsSpo11-4 led to defects in male meiosis, indicating OsSpo11-4 is required for meiosis.
Labs working on this gene
- Chinese Ministry of Science and Technology
- Natural Science Fundation of China
References
- ↑ OsSpo11-4, a Rice Homologue of the Archaeal TopVIA Protein, Mediates Double-Strand DNA Cleavage and Interacts with OsTopVIB
