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| − | {{JaponicaGene|
| + | The rice '''Os12g0622500''' was reported as ''' OsSpo11-4''' in 2011 <ref name="ref1" /> by researchers from the China. |
| − | GeneName = Os12g0622500|
| + | <br> |
| − | Description = Spo11/DNA topoisomerase VI, subunit A family protein|
| + | ==Annotated Information== |
| − | Version = NM_001073839.1 GI:115489639 GeneID:4352826|
| + | ===Gene Symbol=== |
| − | Length = 2971 bp|
| + | *'''Os12g0622500 <=> OsSpo11-4''' |
| − | Definition = Oryza sativa Japonica Group Os12g0622500, complete gene.|
| + | ===Function=== |
| − | Source = Oryza sativa Japonica Group
| + | *'''Spo11''' is essential for initiating meiotic recombination and this function appears conserved among other eukaryotes. |
| | + | ===Mutant=== |
| | + | *'''OsSpo11-4''' exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg2+ and independent of OsTopVIB, despite its interaction with OsTopVIB. We further analyzed the biological function of OsSpo11-4 by RNA interference and found that down-regulated expression of OsSpo11-4 led to defects in male meiosis, indicating '''OsSpo11-4''' is required for meiosis. |
| | | | |
| − | ORGANISM Oryza sativa Japonica Group
| + | ==Labs working on this gene== |
| − | Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
| + | *Chinese Ministry of Science and Technology |
| − | Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
| + | *Natural Science Fundation of China |
| − | clade; Ehrhartoideae; Oryzeae; Oryza.
| + | |
| − | |
| + | ==References== |
| − | Chromosome = [[:category:Japonica Chromosome 12|Chromosome 12]]|
| + | <references> |
| − | AP = Chromosome 12:26804459..26807429|
| + | <ref name="ref1"> |
| − | CDS = 26805466..26806881,26806990..26807037|
| + | OsSpo11-4, a Rice Homologue of the Archaeal TopVIA Protein, Mediates Double-Strand DNA Cleavage and Interacts with OsTopVIB |
| − | GCID = <gbrowseImage1>
| + | </ref> |
| − | name=NC_008405:26804459..26807429 | + | |
| − | source=RiceChromosome12
| + | </references> |
| − | preset=GeneLocation
| + | <br> |
| − | </gbrowseImage1>| | + | |
| − | GSID = <gbrowseImage2>
| + | ==Structured Information== |
| − | name=NC_008405:26804459..26807429
| + | [[Category:Genes]][[Category:Oryza Sativa Japonica Group]][[Category:Japonica Chromosome 12]] |
| − | source=RiceChromosome12
| |
| − | preset=GeneLocation
| |
| − | </gbrowseImage2>| | |
| − | CDNA = <cdnaseq>atggatgattcaacggatgacgattcgtatcatccaagaaaacactatgcttatgatcgtcaggtttcttcaagcagatggcgtaccagccgcgagtatatcagaggtcccggccccgaaactcatactactgagagtgctcaagatggacaggatccacctgctggagtatattcctatggttatttttctggcagtggtaatgatcctcaagttcaaggacactttgttccggagattcaaaagtacaacccttacgtgattttcaaaggtgaacaactcccggttcctatatgggaactgccagaggagaaggtccaagattttcatgataggtactttattgcaaaagacaagagtcgagttgaagccaggaagactctgaataggttgttagaggggaacatcaatacaattgaaaggggacatggatataaattcaatattccaaaatatacagataacatggagtttaatgaggaagtcaaggtttctctagcaaaagcaggcaagaccataagccgttccttttgcaatgcgaatcagcgggaagttgcatctaggactggctataccattgatctaatagaacggacacttggggctggattgaacatctcgaagagaactgtcttatacacaaacaaggatctgtttggggatcaaagtaaatcagatcaagcgatcaatgacatctgcgctttgacaaatatcagaaggggctctttgggtataatagcagctgaaaaaggaattgtagttggaaacattttcctggaattgacaaatggcaaatcgattagttgttctattggagtgcagataccacacaggcttgaccagatcaaagatgtttgtgttgaaataggttcacgcaacatagagtatattcttgttgtggaaaagcatacaatgttgaattatctactagagatggactatcacaccaataacaactgtataattctgacaggatgtggcatgccaaccctccaaacaagggatttcctcagattcttgaaacaacgcactggactacctgtctttggactttgtgatccagatcctgaaggtataagtattcttgctacgtatgctagagggtcttgcaattcagcatatgacaatttcaatatttccgtgccatctatttgttgggttggattgtcatcctcagacatgataaagttgaatttgtctgagaccaactactcacgtttgtctcgcgaggacaaaactatgttgaagaacctttggcaggacgatttgtccgatgtatggaaacgcagaatcgaagaaatgataagttttgacaagaaggcctcttttgaagctattcatagtttggggtttgattattttgcaaccaatttgcttccggatatgattaacaaagtacgagaaggctatgttcaggttcaagagaaaaaagagcctcaagacactgaagccagtgaggactga</cdnaseq>|
| |
| − | AA = <aaseq>MDDSTDDDSYHPRKHYAYDRQVSSSRWRTSREYIRGPGPETHTT ESAQDGQDPPAGVYSYGYFSGSGNDPQVQGHFVPEIQKYNPYVIFKGEQLPVPIWELP EEKVQDFHDRYFIAKDKSRVEARKTLNRLLEGNINTIERGHGYKFNIPKYTDNMEFNE EVKVSLAKAGKTISRSFCNANQREVASRTGYTIDLIERTLGAGLNISKRTVLYTNKDL FGDQSKSDQAINDICALTNIRRGSLGIIAAEKGIVVGNIFLELTNGKSISCSIGVQIP HRLDQIKDVCVEIGSRNIEYILVVEKHTMLNYLLEMDYHTNNNCIILTGCGMPTLQTR DFLRFLKQRTGLPVFGLCDPDPEGISILATYARGSCNSAYDNFNISVPSICWVGLSSS DMIKLNLSETNYSRLSREDKTMLKNLWQDDLSDVWKRRIEEMISFDKKASFEAIHSLG FDYFATNLLPDMINKVREGYVQVQEKKEPQDTEASED</aaseq>|
| |
| − | DNA = <dnaseqindica>1008..2423#2532..2579#gaggggaatttcttgcctctcgctcagatccgttcctccggcgaaaagcgacggcgactttgttgacgctgcggcctcttcccgaccgcgcagcaaaggtgaatctcctcccttcctttgttcatcctgcggtttcctctctccctcttggctcttgctctcttctctacggttttgatgtgcgcgtgccctgtggtccatttgggtgattttgaatcgggcacgtttggatccttggcaaaccaaatcctagccttgcttcatctccagcgcagtgccttgtgatccgctgggctgctgccttgtcagatcccgccaacattgcgccgctgttctgccagatcttgccgtcgctgccacattgcgcaaagaagccgaaagcccttccaatctggccggccacatgctgttgcatgaagcaactggcagaagatatttgtgtttggaattttggggatacttcaaccgaatgagcgagctatcgactgtcttggactaatgagagaattaaacacattttttaccctacacattgttttgtgactattaatcttcctcaggcacatttagtttcaggtcttcaaccaaacagaaccaactcagatatgcctcatcaggcaacaaacatcaaaatatcacgaaactctcaggcagcactttttctcaggcatagctcagggtagcaatcaaaatcagtaacgaagtaattttcatgtaggcccatgataagtgataagtttttagatcaaaggctcaccagcccggcttttatagaaagccaaaatggcaacatgtcatcccgataagtgccaagtgcttatacgggtgcttagaaaatgatcaaagttaacttatccttacctggctaagcaaggtgggagaaagatccaaacgtacacatctccctattgctccatatgaaattggagtattttttaaatcttgcctatctttttttccctatctaatatctattgtttgcttacgatgcagatttgaggtcaccaatggatgattcaacggatgacgattcgtatcatccaagaaaacactatgcttatgatcgtcaggtttcttcaagcagatggcgtaccagccgcgagtatatcagaggtcccggccccgaaactcatactactgagagtgctcaagatggacaggatccacctgctggagtatattcctatggttatttttctggcagtggtaatgatcctcaagttcaaggacactttgttccggagattcaaaagtacaacccttacgtgattttcaaaggtgaacaactcccggttcctatatgggaactgccagaggagaaggtccaagattttcatgataggtactttattgcaaaagacaagagtcgagttgaagccaggaagactctgaataggttgttagaggggaacatcaatacaattgaaaggggacatggatataaattcaatattccaaaatatacagataacatggagtttaatgaggaagtcaaggtttctctagcaaaagcaggcaagaccataagccgttccttttgcaatgcgaatcagcgggaagttgcatctaggactggctataccattgatctaatagaacggacacttggggctggattgaacatctcgaagagaactgtcttatacacaaacaaggatctgtttggggatcaaagtaaatcagatcaagcgatcaatgacatctgcgctttgacaaatatcagaaggggctctttgggtataatagcagctgaaaaaggaattgtagttggaaacattttcctggaattgacaaatggcaaatcgattagttgttctattggagtgcagataccacacaggcttgaccagatcaaagatgtttgtgttgaaataggttcacgcaacatagagtatattcttgttgtggaaaagcatacaatgttgaattatctactagagatggactatcacaccaataacaactgtataattctgacaggatgtggcatgccaaccctccaaacaagggatttcctcagattcttgaaacaacgcactggactacctgtctttggactttgtgatccagatcctgaaggtataagtattcttgctacgtatgctagagggtcttgcaattcagcatatgacaatttcaatatttccgtgccatctatttgttgggttggattgtcatcctcagacatgataaagttgaatttgtctgagaccaactactcacgtttgtctcgcgaggacaaaactatgttgaagaacctttggcaggacgatttgtccgatgtatggaaacgcagaatcgaagaaatgataagttttgacaagaaggcctcttttgaagctattcatagtttggggtttgattattttgcaaccaatttgcttccggatatgattaacaaagtacgagaaggctatgttcaggtatatttctcactcctatagcaacttgtattttttttatattactttgaaattcgtgatccatgagcacactttttcttatatatcagtgtatacattctttgctaggttcaagagaaaaaagagcctcaagacactgaagccagtgaggactgatttggaggactctaatgcagctagagattcagatccataagtttctacaagtaaaagttggagcagcagattggaactgcatgttgatttttgtggatgctcaagcttcactcgtatgtttggcttctgataagtctgtaatagcttagcagcacaattattatagttgtcttctaggtgatcgatctcctaaatacttgcaccactattattgtagttgtcttttatgtgatcgatctcctaagtacctttctgtctgtaatagtttagcaacaccattattatagtactagttatcgtctaggtgatcgatctctcctaagtgcttgcactattgttactgaagttgtcttctagcactattggtactgcagttgttttttcgctgatcg</dnaseqindica>|
| |
| − | Link = [http://www.ncbi.nlm.nih.gov/nuccore/NM_001073839.1 RefSeq:Os12g0622500]|
| |
| − | }}
| |
| − | [[Category:Genes]] | |
| − | [[Category:Japonica mRNA]]
| |
| − | [[Category:Oryza Sativa Japonica Group]] | |
| − | [[Category:Japonica Genes]]
| |
| − | [[Category:Japonica Chromosome 12]] | |
| − | [[Category:Chromosome 12]]
| |
