Difference between revisions of "Os05g0333200"
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==Annotated Information== | ==Annotated Information== | ||
===Function=== | ===Function=== | ||
| − | The d1 mutant, which is deficient for the heterotrimeric G-protein α subunit (G α ) gene of rice, shows dwarfi sm and sets small round seeds. Heterotrimeric G proteins, which are composed of α (G α ),β (G β ) and γ (G γ ) subunits, play a variety of roles in a wide range of physiological responses by transducing extracellular information to intracellular components. Heterotrimeric G proteins act as signal transducer between a receptor (G-protein-coupled receptors, GPCRs) and downstream effectors. G-protein signaling starts with a conformational change of the GPCR upon ligand perception. | + | The d1 mutant, which is deficient for the heterotrimeric G-protein α subunit (G α ) gene of rice, shows dwarfi sm and sets small round seeds. Heterotrimeric G proteins, which are composed of α (G α ),β (G β ) and γ (G γ ) subunits, play a variety of roles in a wide range of physiological responses by transducing extracellular information to intracellular components. Heterotrimeric G proteins act as signal transducer between a receptor (G-protein-coupled receptors, GPCRs) and downstream effectors. G-protein signaling starts with a conformational change of the GPCR upon ligand perception.The GPCR is a guanine-nucleotide-exchange |
| + | factor (GEF) and its activation by the ligand promotes the exchange of GDP for GTP in the associated G α subunit. Subsequently, this complex dissociates into a G α -GTP monomer and a G β γ dimer to regulate downstream effectors. Mammals have multiples of each of the > 20 G α , 5 G β and 11 G γgenes | ||
===Expression=== | ===Expression=== | ||
Revision as of 12:17, 11 May 2014
Please input one-sentence summary here.
Contents
Annotated Information
Function
The d1 mutant, which is deficient for the heterotrimeric G-protein α subunit (G α ) gene of rice, shows dwarfi sm and sets small round seeds. Heterotrimeric G proteins, which are composed of α (G α ),β (G β ) and γ (G γ ) subunits, play a variety of roles in a wide range of physiological responses by transducing extracellular information to intracellular components. Heterotrimeric G proteins act as signal transducer between a receptor (G-protein-coupled receptors, GPCRs) and downstream effectors. G-protein signaling starts with a conformational change of the GPCR upon ligand perception.The GPCR is a guanine-nucleotide-exchange factor (GEF) and its activation by the ligand promotes the exchange of GDP for GTP in the associated G α subunit. Subsequently, this complex dissociates into a G α -GTP monomer and a G β γ dimer to regulate downstream effectors. Mammals have multiples of each of the > 20 G α , 5 G β and 11 G γgenes
Expression
Please input expression information here. Heterotrimeric G proteins, which are composed of α (G α ),β (G β ) and γ (G γ ) subunits, play a variety of roles in a wide range of physiological responses by transducing extracellular information to intracellular components
Evolution
Please input evolution information here.
You can also add sub-section(s) at will. In the shoot hypocotyl, the maximum cell length in gpa1 was not different from that in WT while the cell number was signifi cantly reduced. Our results support the idea that G α s regulate cell proliferation.
Labs working on this gene
Please input related labs here. 1 Department of Bioscience, Fukui Prefectural University, 4-1-1 Matsuoka Kenjyojima, Eiheiji-cho, Yoshida-gun, Fukui, 910-1195 Japan 2 Bioscience and Biotechnology Center, Nagoya University, Chikusa, Nagoya, 464-8604 Japan
References
Please input cited references here. 1. Yuki Izawa;Yoshiyuki Takayanagi;Noriko Inaba;Yuki Abe;Miho Minami;Yukiko Fujisawa;Hisaharu Kato;Shizuka Ohki;Hidemi Kitano;Yukimoto Iwasaki
Function and Expression Pattern of the α Subunit of the Heterotrimeric G Protein in Rice Plant and Cell Physiology, 2010, 51(2): 271-281
2. Kotaro Miura;Masakazu Agetsuma;Hidemi Kitano;Atsushi Yoshimura;Makoto Matsuoka;Steven E. Jacobsen;Motoyuki Ashikari
A metastable DWARF1 epigenetic mutant affecting plant stature in rice Proceedings of the National Academy of Sciences, 2009, 106(27): 11218-11223
3. Lei Wang;Yun-Yuan Xu;Qi-Bin Ma;Dan Li;Zhi-Hong Xu;Kang Chong
Heterotrimeric G protein α subunit is involved in rice brassinosteroid response Cell Research, 2006, 16(12): 916-922
4. Miyako Ueguchi-Tanaka;Yukiko Fujisawa;Masatomo Kobayashi;Motoyuki Ashikari;Yukimoto Iwasaki;Hidemi Kitano;Makoto Matsuoka
Rice dwarf mutant d1, which is defective in the α subunit of the heterotrimeric G protein, affects gibberellin signal transduction Proceedings of the National Academy of Sciences, 2000, 97(21): 11638-11643
5. Motoyuki Ashikari;Jianzhong Wu;Masahiro Yano;Takuji Sasaki;and Atsushi Yoshimura
Rice gibberellin-insensitive dwarf mutant gene Dwarf 1 encodes the α-subunit of GTP-binding protein Proceedings of the National Academy of Sciences, 1999, 96(18): 10284-10289
6. Yukiko Fujisawa;Teruhisa Kato;Shizuka Ohki;Atsushi Ishikawa;Hidemi Kitano;Takuji Sasaki;Tadashi Asahi;and Yukimoto Iwasaki
Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice Proceedings of the National Academy of Sciences, 1999, 96(13): 7575-7580
7. Atsushi Ishikawa;Hitoshi Tsubouchi;Yukimoto Iwasaki;Tadashi Asahi
Molecular Cloning and Characterization of a cDNA for the α Subunit of a G Protein from Rice Plant and Cell Physiology, 1995, 36(2): 353-359
Structured Information
| Gene Name |
Os05g0333200 |
|---|---|
| Description |
Guanine nucleotide-binding protein alpha-1 subunit (GP-alpha-1) |
| Version |
NM_001061761.1 GI:115463252 GeneID:4338448 |
| Length |
4020 bp |
| Definition |
Oryza sativa Japonica Group Os05g0333200, complete gene. |
| Source |
Oryza sativa Japonica Group ORGANISM Oryza sativa Japonica Group
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP
clade; Ehrhartoideae; Oryzeae; Oryza.
|
| Chromosome | |
| Location |
Chromosome 5:15587381..15591400 |
| Sequence Coding Region |
15587656..15587821,15587986..15588065,15588143..15588202,15588289..15588382,15588459..15588593 |
| Expression | |
| Genome Context |
<gbrowseImage1> name=NC_008398:15587381..15591400 source=RiceChromosome05 preset=GeneLocation </gbrowseImage1> |
| Gene Structure |
<gbrowseImage2> name=NC_008398:15587381..15591400 source=RiceChromosome05 preset=GeneLocation </gbrowseImage2> |
| Coding Sequence |
<cdnaseq>atgtccgtgcttacctgtgtgcttgataacatgggctcatcctgtagcagatctcattctttaagtgaggctgaaacaaccaaaaatgcaaaatctgcagacattgacaggcgaattttgcaagagacaaaagcagagcaacacatccacaagctcttacttcttggtgcgggagaatcagggaagtctacgatatttaaacagattaagctccttttccaaactggctttgatgaggcagaacttaggagctacacatcagttatccatgcaaacgtctatcagacaattaaaatactatatgaaggagcaaaagaactctcacaagtggaatcagattcctcaaagtatgttatatccccagataaccaggaaattggagaaaaactatcagatattgatggcaggttggattatccactgctgaacaaagaacttgtactcgatgtaaaaaggttatggcaagacccagccattcaggaaacttacttacgtggaagtattctgcaacttcctgattgtgcacaatacttcatggaaaatttggatcgattagctgaagcaggttatgtgccaacaaaggaggatgtgctttatgcaagagtacggacaaatggtgttgtacaaatacaatttagtcctgttggagaaaacaaaagaggtggagaggtatataggttgtatgatgtaggaggccagaggaatgagaggagaaagtggattcatctttttgaaggtgttaatgcggtaatcttttgtgctgccattagcgaatatgatcagatgctatttgaagatgagacaaaaaacagaatgatggagaccaaggaactctttgactgggttttaaagcaaagatgttttgagaaaacatcattcattctgtttctcaacaaatttgatatattcgagaagaaaatacaaaaggttcctttaagtgtgtgcgagtggtttaaagactaccagcctattgcacctgggaaacaggaggttgaacatgcatatgagtttgtcaagaagaagtttgaagagctctacttccagagcagcaagcctgaccgtgtggaccgcgtcttcaaaatctacagaactacggccctagaccagaaacttgtaaagaagacattcaagttgattgatgagagcatgagacgctccagggaaggaacttga</cdnaseq> |
| Protein Sequence |
<aaseq>MSVLTCVLDNMGSSCSRSHSLSEAETTKNAKSADIDRRILQETK AEQHIHKLLLLGAGESGKSTIFKQIKLLFQTGFDEAELRSYTSVIHANVYQTIKILYE GAKELSQVESDSSKYVISPDNQEIGEKLSDIDGRLDYPLLNKELVLDVKRLWQDPAIQ ETYLRGSILQLPDCAQYFMENLDRLAEAGYVPTKEDVLYARVRTNGVVQIQFSPVGEN KRGGEVYRLYDVGGQRNERRKWIHLFEGVNAVIFCAAISEYDQMLFEDETKNRMMETK ELFDWVLKQRCFEKTSFILFLNKFDIFEKKIQKVPLSVCEWFKDYQPIAPGKQEVEHA YEFVKKKFEELYFQSSKPDRVDRVFKIYRTTALDQKLVKKTFKLIDESMRRSREGT</aaseq> |
| Gene Sequence |
<dnaseqindica>3580..3745#3336..3415#3199..3258#3019..3112#2808..2942#2573..2628#1769..1870#1578..1685#946..1023#708..797#589..626#267..339#76..168#ggatcctgagatctagacgtcaacgtgcttcctggaaagagagaggctcaggcatgagagcatacctctaaaataatgtccgtgcttacctgtgtgcttgataacatgggctcatcctgtagcagatctcattctttaagtgaggctgaaacaaccaaaaatgcaaaagtaagttagcactcggacttattgaacaagtaaatgctaactcaattcttgatttgagagttgccacatttggtttcttctaattcagctggtaacagtctgcagacattgacaggcgaattttgcaagagacaaaagcagagcaacacatccacaagctcttacttcttggtattgctaactttcccaaatttaagtggtcattttccttgtcacaattatctgtgctacctttagtatctattggttcagaaaattaattgtttatgttgttcctatttacctctataaaaaaacctttctcatgttatttccaaaaaaaaagaagataaataaatgtatcctagaaatttttagtttgaacttgttctcaatgtggatccatccttctttctctctctcaattgcttctgttttaaggtgcgggagaatcagggaagtctacgatatttaaacaggtgatgaatgttatattccatggagaatcataatccgtacgccgctagttagtctgatgtattcttactgttcacctgcagattaagctccttttccaaactggctttgatgaggcagaacttaggagctacacatcagttatccatgcaaacgtctatcagacaattaaagtatgcaatactggaaagggtgtgtcttttttttcttattgcaaagtggggattatgtaggagattcgactagggatttgtattctgttcataaggaaatgcgttcatacttttcctttttgtcgagtaatgtgttaaatgttaacagatactatatgaaggagcaaaagaactctcacaagtggaatcagattcctcaaagtatgttatatccccagataaccaggtttgtgcttactctttactcaacagttaaagctaaatctgtgcatatgaacatgtcttgttaaatctgggaatacaaacattttgatttgcaacatttctgttgtagtcaagctgctcggctctatgttttaacctgttaagaccttgtagactgtgctcggctctattgtagtcttatattttacacggtcattctataatgaaaacttgaaaaagatatctattgaaccgtacaatgtactgaacaaagtagaaaagaacaatgagattttgtaacatttattcttccttgtttatttgattgcttcagacaattgttgatatgctaaaaataacttggtatcaaatgtgggtgttataagattcaatttttttctcaaccaggttaaaaaaagtatacctttgtgcatttaccttgttccgttgctttggaactttaaaggaaaactgacttttcttaggcattgaaagacaaatatcaccagtttcacactgtacaccttaccaaccaattttgtttcttagatgtcatttactttgtcatatcatcaggaaattggagaaaaactatcagatattgatggcaggttggattatccactgctgaacaaagaacttgtactcgatgtaaaaaggttatggcaagacccagccattcaggtgaaaacaaatagccattcaaatcttttgaagttatatagttttcctggccaggtgtgctgaagcaatgctctatactgtaggaaacttacttacgtggaagtattctgcaacttcctgattgtgcacaatacttcatggaaaatttggatcgattagctgaagcaggttatgtgccaacaaaggtgtgctgtccatgttcatagacaattatttacatattctcagatatttgtgctgacaccatttcatgttgatttttagtctacttagtcagaggttgtcaaatggttaactatgtgtactgagtcagaggttgccaaatagttttaaaagatgggcatatgtttatccttatcttttaaataatattggaggctatcctttaaaattcaatattagggaggagaaactattattctaccgttattacgcagtctacataacgaaggtaaaaaatgtccctgtgaaacatagggtgcaaaactgctgtgaataaaactctacttatctaagcaccttgagcttttgagttcccacatattaatcttatgacactagcatatattttttttgttcagttccttcaataagttgcaaaccacaaatatgatcactgtaccatccacttttgcaaccatttcccgtcatttcttaagcatagaaaattgtttgtcacttgtttaagtccacactgcatcaaaattccaattaacattgtgtgtgctaagtgaagatatgactccatatttctgcatttagcagtctgatggataatttgtgattgtaccttgtctaatggttcgtttgaaaggctggtagttgatcttccatacttaagaatgcttgcagtattatagttgtcaatattatgagtcattttgcaggaggatgtgctttatgcaagagtacggacaaatggtgttgtacaaatacaatttaggtaatctgctgacactattttttgcacatttttttgctggttgctctactatgtacagaacgacaagttgaagtcctttttttctcccctttcacttctaagatatgacctgagaggttctgaatgtagctgttttaagatgagttgaatcatctagttaactgggtttctttctgcagtcctgttggagaaaacaaaagaggtggagaggtatataggttgtatgatgtaggaggccagaggaatgagaggagaaagtggattcatctttttgaaggtgttaatgcggtaatcttttgtgctgccattagcgagtaagtacaatttttttgattgttgaacttatcctaatctgctaagttcttctcataggcttcttgttcatttcagatatgatcagatgctatttgaagatgagacaaaaaacagaatgatggagaccaaggaactctttgactgggttttaaagcaaagatgttttgaggtctgcatgcatccatctctgcaacctttgtgctcatgctttttttctcattttgaaactaattacggtgctatattgaccatcagaaaacatcattcattctgtttctcaacaaatttgatatattcgagaagaaaatacaaaaggtaaggcctgctctttgtaccaatgcatagtttagtactaaatgttaccaacatttatgtttacgctggttacgtaggttcctttaagtgtgtgcgagtggtttaaagactaccagcctattgcacctgggaaacaggaggttgaacatgcatatgagtgagtgcactactcgccctctcagatgaacatgggcatttggccatttgtaatgttgctgcatggtgcacttatatgccttgataagtttttccattctaatgttatatagtatcaaacgttcatcattactgtggcttatggtctggagtgacgttttacaggtttgtcaagaagaagtttgaagagctctacttccagagcagcaagcctgaccgtgtggaccgcgtcttcaaaatctacagaactacggccctagaccagaaacttgtaaagaagacattcaagttgattgatgagagcatgagacgctccagggaaggaacttgattcagagctaagactaggttgtaagtcacacagggaaggtaattaggacggcgagaggaacaaagtttcacactgtcacagctttatctgttgtaattcttttacacgtggaccattgattgatcttttggttcttactgtgggctgttcaggtctgtaccctattttttgttctctagttagccattgtgcaaattttccttgaatcagattctctacctgttgtctatgtgtgttatcttggtctgttaatttgcatagcccacttgttcatt</dnaseqindica> |
| External Link(s) |
