Difference between revisions of "Os07g0580500"
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===Function=== | ===Function=== | ||
| − | + | *A conserved function of '''OsBZR1''' and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice. | |
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| − | === | + | ===Mutant=== |
| − | + | *Suppressing '''OsBZR1''' expression by RNAi resulted in dwarfism, erect leaves, reduced BR sensitivity, and altered BR-responsive gene expression in transgenic rice plants, demonstrating an essential role of '''OsBZR1''' in BR responses in rice. | |
| − | + | *Mutation of a putative 14-3-3-binding site of '''OsBZR1''' abolished its interaction with the 14-3-3 proteins in yeast and in vivo. Such mutant '''OsBZR1''' proteins suppressed the phenotypes of the Arabidopsis bri1–5 mutant and showed an increased nuclear distribution compared with the wild-type protein, suggesting that 14-3-3proteins directly inhibit '''OsBZR1''' function at least in part by reducing its nuclear localization. | |
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==Labs working on this gene== | ==Labs working on this gene== | ||
*Key Laboratory of Photosynthesis and Environmental Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; | *Key Laboratory of Photosynthesis and Environmental Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; | ||
Latest revision as of 15:21, 8 November 2016
The rice Os07g0580500 was reported as OsBZR1 in 2007 [1] by researchers from the China.
Contents
Annotated Information
Gene Symbol
- Os07g0580500 <=> OsBZR1
Function
- A conserved function of OsBZR1 and an important role of 14-3-3 proteins in brassinosteroid signal transduction in rice.
Mutant
- Suppressing OsBZR1 expression by RNAi resulted in dwarfism, erect leaves, reduced BR sensitivity, and altered BR-responsive gene expression in transgenic rice plants, demonstrating an essential role of OsBZR1 in BR responses in rice.
- Mutation of a putative 14-3-3-binding site of OsBZR1 abolished its interaction with the 14-3-3 proteins in yeast and in vivo. Such mutant OsBZR1 proteins suppressed the phenotypes of the Arabidopsis bri1–5 mutant and showed an increased nuclear distribution compared with the wild-type protein, suggesting that 14-3-3proteins directly inhibit OsBZR1 function at least in part by reducing its nuclear localization.
Labs working on this gene
- Key Laboratory of Photosynthesis and Environmental Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China;
- Department of Plant Biology, Carnegie Institution, Stanford, CA 94305; and ‡Department of Plant Pathology, Plant Molecular;
- Cellular Biology Program, University of Florida, Gainesville, FL 32611
References
- ↑ Functions of OsBZR1 and 14-3-3 proteins in brassinosteroid signaling in rice