Os01g0125800
The rice Os01g0125800 was reported as AIP1 in 2013 [1] by researchers from China.
Contents
Annotated Information
Figure 2. The F-actin level is increased in OsAIP1 RNAi pollen grains but reduced in OsAIP1 OE pollen grains.[1].
Gene Symbol
- Os01g0125800 <=> OsAIP1,AIP1
Function
- Actin-interacting protein 1 (AIP1) has been shown to be an important factor by acting coordinately with actin-depolymerizing factor (ADF)/cofilin in promoting actin depolymerization, the rate-limiting factor in actin turnover.
- Specific down-regulation of OsAIP1 increased the level of filamentous actin and reduced actin turnover, whereas over-expression of OsAIP1 induced fragmentation and depolymerization of actin filaments and enhanced actin turnover.
- OsAIP1 acts coordinately with ADF and profilin to induce massive net actin depolymerization, indicating that AIP1 plays a major role in the turnover of actin, which is required to optimize F-actin levels in plants.
Phenotypic analysis
- The actin cytoskeleton appeared to form a uniformly distributed network in control pollen grains (Figure 2a), but appeared fragmented in OsAIP1 over-expression pollen grains (Figure 2b), suggesting that OsAIP1 over-expression induced actin depolymerization.
- By contrast, actin filaments became denser and more highly bundled in OsAIP1 RNAi pollen grains (Figure 2c). The F-actin level was decreased in OsAIP1 over-expression pollen grains but increased in OsAIP1 RNAi pollen grains (Figure 2d), and the F-actin level inversely correlated with the amount of OsAIP1 transcript, suggesting that OsAIP1 inhibits actin polymerization.
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Labs working on this gene
- Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
- University of Chinese Academy of Sciences, Beijing 100049, China
- Institute of Crop and Nuclear Technology Utilization, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China
- Hunan Agricultural University, Changsha, 410128, China
