e.g. IL6;  SIRT6; 

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  • Browse the database by Factors: Clicking the “Search” button, you will browse the corresponding datasets in the ChIP-seq database. You can limit the search scope by using advanced search function (e.g. Factors class, Factors, Cell types etc.)
  • Visualization: Tick the dataset of interest in the table, enter a gene name or genome cordinate, then click “Go to WashU Epigenome Browser” for visualizing the selected data.

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Species
Cell Type
Senescence Type
Factor
Technology
GEO
Doi
Publication
Homo sapiensHuman mesenchymal progenitor cellsinduced senescenceH3K4me3WRN -/- EP vs WRN -/- LP vs LMNA G608G/+ EP vs LMNA G608G/+ LP vs LMNA G608G/G608G EP vs LMNA G608G/G608G LP vs WT EP vs WT LPThe paper with the data has not yet been published.
Homo sapiensHuman fetal lung fibroblats (Uninduced Proliferative)oncogene-induced senenscenceH3K9me3OISD0 vs OISD2 vs OISD6 vs OIS D10GSE13030610.1016/j.molcel.2020.03.0074D Genome Rewiring During Oncogene-Induced and Replicative Senescence
Homo sapiensHuman mesenchymal progenitor cellsinduced senescenceH3K9me3WT vs BMAL1 KOThe paper with the data has not yet been published.BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates
Homo sapiensHuman mesenchymal progenitor cellsalleviated senescenceATAC-seqWT vs APOE KOThe paper with the data has not yet been published.Destabilizing heterochromatin by APOE mediates senescence
Homo sapiensHuman mesenchymal progenitor cellsalleviated senescenceDamID-seqWT vs APOE KOThe paper with the data has not yet been published.Destabilizing heterochromatin by APOE mediates senescence
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