e.g. IL6;  SIRT6; 

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e.g. IL6;  SIRT6; 

Transcriptomics

The transcriptomics module catalogs genome-wide transcriptomic changes related to aging. This contains a list of differentially expressed genes (DEGs), fold changes, and descriptions of underlying experimental conditions.

Latest Articles

  • 1. Ma, S., Sun, S., Geng, L., Song, M., Wang, W., Ye, Y., Ji, Q., Zou, Z., Wang, S., He, X., et al. (2020). Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging. Cell. 180, 984–1001.e22. https://doi.org/10.1016/j.cell.2020.02.008.
  • 2. Wang, S., Zheng, Y., Li, J., Yu, Y., Zhang, W., Song, M., Liu, Z., Min, Z., Hu, H., Jing, Y., et al. (2020). Single-Cell Transcriptomic Atlas of Primate Ovarian Aging. Cell. 180, 585–600.e19. https://doi.org/10.1016/j.cell.2020.01.009.
  • 3. Bi, S., Liu, Z., Wu, Z., Wang, Z., Liu, X., Wang, S., Ren, J., Yao, Y., Zhang, W., Song, M., et al. (2020). SIRT7 Antagonizes Human Stem Cell Aging as A Heterochromatin Stabilizer. Protein Cell. 11, 483–504. https://doi.org/10.1007/s13238-020-00728-4.
  • 4. Hu, H., Ji, Q., Song, M., Ren, J., Liu, Z., Wang, Z., Liu, X., Yan, K., Hu, J., Jing, Y., et al. (2020). ZKSCAN3 Counteracts Cellular Senescence by Stabilizing Heterochromatin. Nucleic Acids Res. 48, 6001–6018. https://doi.org/10.1093/nar/gkaa425.
  • 5. Zhang, W., Zhang, S., Yan, P., Ren, J., Song, M., Li, J., Lei, J., Pan, H., Wang, S., Ma, X., et al. (2020). A Single-cell Transcriptomic Landscape of Primate Arterial Aging. Nat. Commun. 11, 2202. https://doi.org/10.1038/s41467-020-15997-0.