The RNA-seq module in the Aging Atlas database collects RNA-seq data sets from published articles related to aging research, including transcriptome changes observed under specific genetic intervention (overexpression, knockout, etc.), and the changes in gene expression of specific tissues or organs during physiological and pathological aging.
1. On the RNA-seq sub-page, users can search for differential expressed genes (DEGs) by gene name. The search results include basic information of DEGs (Gene Summary), RNA-seq results (RNA-seq) and gene ontology information (Ontologies) three parts.
2. Gene Summary: The basic gene information part including gene ID, alias, the description related to the aging process, and links to the websites of GeneCards, GenAge and UniProt.
3. RNA-seq: RNA-seq data results including species, cells/tissues, upstream regulatory factors, gene expression changes, and data source article information. Users can filter and download search results. The website provides two download formats, csv and txt.
4. Ontologies: The gene ontology information part including biological process, cellular component and molecular function, each result can be linked to the AmiGO website for detailed information.