Accession

PRJCA001180

Title

Dynamic m6A and m6Am methylome across diverse human tissues

Relevance

Medical

Data types

Epigenomics
Transcriptome or Gene expression
Raw sequence reads

Organisms

Mus musculus
Homo sapiens

Description

N6-methyladenosine (m6A), the most abundant internal mRNA modification, and N6,2'-O-dimethyladenosine (m6Am), found at the first-transcribed nucleotide, are two examples of dynamic and reversible epitranscriptomic marks. In this study, we measured the level of m6A and m6Am and provide the first transcriptome-wide characterization of m6A and m6Am methylome in human tissues.

Sample scope

Multiisolate

Release date

2020-01-08

Publication

PubMed ID	Article title	Journal name	DOI	Year
31676230	Landscape and regulation of m6A and m6Am methylome across human and mouse tissues	Molecular Cell	10.1016/j.molcel.2019.09.032	2020

Grants

Agency	program	Grant ID	Grant title
National Natural Science Foundation of China (NSFC)		2182570
National Natural Science Foundation of China (NSFC)		91740112

Submitter

li kai (li_kai@pku.edu.cn)

Organization

Peking University

Submission date

2018-12-24

Project Data

Resource name	Description
BioSample (162) show	-
SAMC106578	Lung-4-4-Input
SAMC106577	Lung-4-4-IP
SAMC106576	Lung-2-4-Input-human
SAMC106575	Lung-2-4-IP-human
SAMC106574	Cerebellum-7-4-Input
SAMC106573	Cerebellum-7-4-IP
SAMC106572	Jurkat-2-IP
SAMC106571	Jurkat-2-Input
SAMC106570	Jurkat-1-IP
SAMC106569	Jurkat-1-Input
SAMC106568	U20S-IP
SAMC106567	U20S-Input
SAMC106566	WPMY-1-2-IP
SAMC106565	WPMY-1-2-Input
SAMC106564	WPMY-1-1-IP
SAMC106563	WPMY-1-1-Input
SAMC106562	U251-IP
SAMC106561	U251-Input
SAMC106560	K562-2-IP
SAMC106559	K562-2-Input
SAMC106558	K562-1-IP
SAMC106557	K562-1-Input
SAMC106556	HT29-IP
SAMC106555	HT29-Input
SAMC106554	Hela-2-IP
SAMC106553	Hela-2-Input
SAMC106552	Hela-1-IP
SAMC106551	Hela-1-Input
SAMC106550	GOS-3-2-IP
SAMC106549	GOS-3-2-Input
SAMC106548	GOS-3-1-IP
SAMC106547	GOS-3-1-Input
SAMC106545	Lung-2-4-IP
SAMC106544	Lung-2-4-Input
SAMC106543	Lung-1-4-IP
SAMC106542	Lung-1-4-Input
SAMC106541	Heart-1-4-IP
SAMC106540	Heart-1-4-Input
SAMC106539	Liver-1-4-IP
SAMC106538	Liver-1-4-Input
SAMC069794	Hypothalamus-2-5-IP
SAMC069793	Hypothalamus-2-5-Input
SAMC069792	Brainstem-2-5-IP
SAMC069791	Brainstem-2-5-Input
SAMC069790	Cerebellum-2-5-IP
SAMC069789	Cerebellum-2-5-Input
SAMC069788	Cerebrum-2-5-IP
SAMC069787	Cerebrum-2-5-Input
SAMC069786	Liver-2-5-IP
SAMC069785	Liver-2-5-Input
SAMC069784	Lung-2-5-IP
SAMC069783	Lung-2-5-Input
SAMC069782	Spleen-2-5-IP
SAMC069781	Spleen-2-5-Input
SAMC069780	Heart-2-5-IP
SAMC069779	Heart-2-5-Input
SAMC069778	Hypothalamus-1-5-IP
SAMC069777	Hypothalamus-1-5-Input
SAMC069776	Brainstem-1-5-IP
SAMC069775	Brainstem-1-5-Input
SAMC069774	Cerebellum-1-5-IP
SAMC069773	Cerebellum-1-5-Input
SAMC069772	Cerebrum-1-5-IP
SAMC069771	Cerebrum-1-5-Input
SAMC069770	Liver-1-5-IP
SAMC069769	Liver-1-5-Input
SAMC069768	Lung-1-5-IP
SAMC069767	Lung-1-5-Input
SAMC069766	Spleen-1-5-IP
SAMC069765	Spleen-1-5-Input
SAMC069764	Heart-1-5-IP
SAMC069763	Heart-1-5-Input
SAMC069762	293T-0-3-Input
SAMC069761	293T-0-3-IP
SAMC069760	Rectum-4-2-Input
SAMC069759	Rectum-4-2-IP
SAMC069758	Esophagus-4-2-Input
SAMC069757	Esophagus-4-2-IP
SAMC069756	Rectum-5-3-Input
SAMC069755	Rectum-5-3-IP
SAMC069754	Appendix-5-3-Input
SAMC069753	Appendix-5-3-IP
SAMC069752	Jejunum-5-3-Input
SAMC069751	Jejunum-5-3-IP
SAMC069750	Cerebrum-6-3-Input
SAMC069749	Cerebrum-6-3-IP
SAMC069748	Jejunum-4-2-Input
SAMC069747	Jejunum-4-2-IP
SAMC069746	Muscle-3-2-Input
SAMC069745	Muscle-3-2-IP
SAMC069744	Esophagus-3-2-Input
SAMC069743	Esophagus-3-2-IP
SAMC069742	Colon-3-2-Input
SAMC069741	Colon-3-2-IP
SAMC069740	Appendix-3-2-Input
SAMC069739	Appendix-3-2-IP
SAMC069738	Spleen-3-2-Input
SAMC069737	Spleen-3-2-IP
SAMC069736	Urinary_bladder-2-1-Input
SAMC069735	Urinary_bladder-2-1-IP
SAMC069734	Tongue-2-1-Input
SAMC069733	Tongue-2-1-IP
SAMC069732	Spleen-2-1-Input
SAMC069731	Spleen-2-1-IP
SAMC069730	Lung-2-1-Input
SAMC069729	Lung-2-1-IP
SAMC069728	Aorta-1-1-IP
SAMC069727	Aorta-1-1-Input
SAMC069726	Spleen-1-1-Input
SAMC069725	Spleen-1-1-IP
SAMC069724	Heart-1-1-Input
SAMC069723	Heart-1-1-IP
SAMC069722	Adipose-1-1-Input
SAMC069721	Adipose-1-1-IP
SAMC052794	Urinary bladder
SAMC052793	Urinary bladder
SAMC052792	Urinary bladder
SAMC052791	Urinary bladder
SAMC052790	Trachea
SAMC052789	Trachea
SAMC052788	Thyroid gland
SAMC052787	Thyroid gland
SAMC052786	Thyroid gland
SAMC052785	Thyroid gland
SAMC052784	Testis
SAMC052783	Testis
SAMC052782	Stomach
SAMC052781	Stomach
SAMC052780	Stomach
SAMC052779	Stomach
SAMC052778	Skin
SAMC052777	Skin
SAMC052776	Skin
SAMC052775	Skin
SAMC052774	Prostate
SAMC052773	Prostate
SAMC052772	Muscle
SAMC052771	Muscle
SAMC052770	Lung
SAMC052769	Lung
SAMC052768	Liver
SAMC052767	Liver
SAMC052766	Hypothalamus
SAMC052765	Hypothalamus
SAMC052764	Heart
SAMC052763	Heart
SAMC052762	Duodenum
SAMC052761	Duodenum
SAMC052760	Cerebrum
SAMC052759	Cerebrum
SAMC052758	Cerebellum
SAMC052757	Cerebellum
SAMC052756	Brainstem
SAMC052755	Brainstem
SAMC052754	Aorta
SAMC052753	Aorta
SAMC052752	Adrena gland
SAMC052751	Adrenal gland
SAMC052750	293T cell
SAMC052749	293T cell
SAMC052748	293T cell
SAMC052747	293T cell
GSA (2)	-
CRA001315	Landscape and regulation of m6A and m6Am methylome across human tissues and cell lines
CRA001962	Landscape and regulation of m6A and m6Am methylome across mouse tissues