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Accession PRJCA005395
Title The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells
Relevance Medical
Data types Epigenomics
Transcriptome or Gene expression
Raw sequence reads
Organisms Homo sapiens
Description In vitro induction of human primordial germ cell-like cells (hPGCLCs) provides an ideal platform to recapitulate hPGC development. However, the detailed molecular mechanisms regulating the induction of hPGCLCs remain largely uncharacterized. Here, we profiled the chromatin accessibility and transcriptome dynamics throughout the process of hPGCLC induction.
Sample scope Synthetic
Release date 2021-06-07
Publication
PubMed ID Article title Journal name DOI Year
33930315 10.1016/j.stemcr.2021.03.032
33613110 10.7150/ijbs.55873
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) Key Program 2017YFA0105001
National Natural Science Foundation of China (NSFC) Key Program 2016YFC1000606
National Natural Science Foundation of China (NSFC) 31671544
National Natural Science Foundation of China (NSFC) 31601208
National Natural Science Foundation of China (NSFC) 31970787
National Natural Science Foundation of China (NSFC) 31700676
National Natural Science Foundation of China (NSFC) 32000579
National Natural Science Foundation of China (NSFC) 82071711
Guangzhou Regenerative Medicine and Health Guangdong Laboratory 2018GZR110104002
Guangzhou science and technology project key project topic 201904020031
Clinical Innovation Research Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory 2018GZR0201003
Outstanding Scholar Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory 2018GZR110102004
Submitter Xiaoyang Zhao (zhaoxiaoyang@smu.edu.cn)
Organization Southern Medical University
Submission date 2021-06-07

Project Data

Resource name Description
BioSample (77)  show -