| Accession | PRJCA006189 | ||||||||||||||||||||||||||||||||||||||||
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| Title | Methionine Deficiency Facilitates Antitumor Immunity by Altering m6A Methylation of Immune Checkpoint Transcripts | ||||||||||||||||||||||||||||||||||||||||
| Relevance | Medical | ||||||||||||||||||||||||||||||||||||||||
| Data types |
Epigenomics
Transcriptome or Gene expression Raw sequence reads |
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| Organisms |
Mus musculus
Homo sapiens |
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| Description | Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumor immunity are molecularly intertwined. Here, we systematically analyzed the correlation between methionine metabolism and anti-tumor immunity by performing high-throughout squencing and corresponding experiment. | ||||||||||||||||||||||||||||||||||||||||
| Sample scope | Multiisolate | ||||||||||||||||||||||||||||||||||||||||
| Release date | 2021-09-16 | ||||||||||||||||||||||||||||||||||||||||
| Grants |
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| Submitter | Rui-hua Xu (xurh@sysucc.org.cn) | ||||||||||||||||||||||||||||||||||||||||
| Organization | Sun Yat-sen University | ||||||||||||||||||||||||||||||||||||||||
| Submission date | 2021-08-16 |