| Accession | SAMC1930174 |
|---|---|
| Accession in Other Database | GSA-Human: HRS303384 |
| Sample name | HT29_Rep1_Input |
| Title | Replication 1 of RNAseq for HT29 cell line |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | Replication 1 of RNAseq for HT29 cell line |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA001424 in the GSA-Human system. |
| Release date | 2021-10-09 |
| BioProject Accession | PRJCA006189 |
| Submitter | Rui-hua Xu (xurh@sysucc.org.cn) |
| Organization | Sun Yat-sen University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA001424 (Controlled Access) | Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumor immunity are molecularly intertwined. Here, we performed RIP-seq to show that methionine-mediated m6A methylation in tumor cells promoted the translation of PD-L1 and VISTA via the m6A-specific binding protein YTHDF1. |