Accession | SAMC1930178 |
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Accession in Other Database | GSA-Human: HRS303385 |
Sample name | HT29_Rep1_IP |
Title | Replication 1 of RIP-seq for HT29 cell line |
Sample type | Human sample |
Organism | Homo sapiens |
Description | Replication 2 of RIP-seq for HT29 cell line |
Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA001424 in the GSA-Human system. |
Release date | 2021-10-09 |
BioProject Accession | PRJCA006189 |
Submitter | Rui-hua Xu (xurh@sysucc.org.cn) |
Organization | Sun Yat-sen University |
Submission date | 2023-06-18 |
Resource name | Description |
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GSA-Human (1) | - |
HRA001424 (Controlled Access) | Methionine metabolism is involved in a myriad of cellular functions, including methylation reactions and redox maintenance. Nevertheless, it remains unclear whether methionine metabolism, RNA methylation and antitumor immunity are molecularly intertwined. Here, we performed RIP-seq to show that methionine-mediated m6A methylation in tumor cells promoted the translation of PD-L1 and VISTA via the m6A-specific binding protein YTHDF1. |