| Accession |
PRJCA010235 |
| Title |
Rencal cell carcinoma |
| Relevance |
Medical |
| Data types |
Epigenomics
Exome
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Fumarate Hydratase Deficient Renal Cell Carcinoma (FH-RCC), characterized as carrying pathogenic germline or somatic FH alteration, is a rare subtype of renal cell carcinoma manifested with high invasive and early metastatic potential. However, the distinct multi-omics features and evolutionary relationships between metastatic and primary lesions are still unclear. In this study, whole-exome, RNA and DNA-methylation sequencing were performed for primary-metastatic paired specimens from 19 FH-RCC cases. |
| Sample scope |
Multiisolate |
| Release date |
2023-04-13 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 37131267
|
Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase-deficient renal cell carcinoma
|
Genome Medicine
|
10.1186/s13073-023-01182-7
|
2023
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| No funding support
|
|
|
|
|
|
| Submitter |
Hao
Zeng (drliangjiayu@163.com)
|
| Organization |
Sichuan University |
| Submission date |
2022-06-24 |
