Accession PRJCA010235
Title Rencal cell carcinoma
Relevance Medical
Data types Epigenomics
Exome
Transcriptome or Gene expression
Organisms Homo sapiens
Description Fumarate Hydratase Deficient Renal Cell Carcinoma (FH-RCC), characterized as carrying pathogenic germline or somatic FH alteration, is a rare subtype of renal cell carcinoma manifested with high invasive and early metastatic potential. However, the distinct multi-omics features and evolutionary relationships between metastatic and primary lesions are still unclear. In this study, whole-exome, RNA and DNA-methylation sequencing were performed for primary-metastatic paired specimens from 19 FH-RCC cases.
Sample scope Multiisolate
Release date 2023-04-13
Publication
PubMed ID Article title Journal name DOI Year
37131267 Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase-deficient renal cell carcinoma Genome Medicine 10.1186/s13073-023-01182-7 2023
Grants
Agency program Grant ID Grant title
No funding support
Submitter Hao    Zeng  (drliangjiayu@163.com)
Organization Sichuan University
Submission date 2022-06-24

Project Data

Resource name Description