| Accession | SAMC2174830 |
|---|---|
| Accession in Other Database | GSA-Human: HRS397410 |
| Sample name | FH48M2 |
| Title | WES FH48M2 |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | WES Metastatic lesions |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA002591 in the GSA-Human system. |
| Release date | 2024-06-24 |
| BioProject Accession | PRJCA010235 |
| Submitter | Hao Zeng (kucaizeng@163.com) |
| Organization | Sichuan University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA002591 (Controlled Access) | Fumarate Hydratase Deficient Renal Cell Carcinoma (FH-RCC), characterized as carrying pathogenic germline or somatic FH alteration, is a rare subtype of renal cell carcinoma manifested with high invasive and early metastatic potential. However, the distinct multi-omics features and evolutionary relationships between metastatic and primary lesions are still unclear. In this study, whole-exome, RNA and DNA-methylation sequencing were performed for primary-metastatic paired specimens from 19 FH-RCC cases. |