| Accession | SAMC1398164 |
|---|---|
| Accession in Other Database | GSA-Human: HRS051075 |
| Sample name | M_miRNA04 |
| Title | miRNA isolated from peripheral blood |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | samples from moderate patients |
| Attributes | *Only part of the sample information is displayed on this page because the related dataset HRA000238 has not yet been registered in the Human Genetic Resource Management Platform of MOST. |
| Release date | 2020-09-10 |
| BioProject Accession | PRJCA003095 |
| Submitter | Wenru Su (suwr3@mail.sysu.edu.cn) |
| Organization | Zhongshan Ophthalmic Center,Sun Yat-sen University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA000238 (Open Access) | We collected peripheral blood samples of 6 severe COVID-19 patients, 6 moderate COVID-19 patients and 4 healthy controls and performed multi-transcriptome sequencing of ncRNAs and mRNAs. Several miRNAs were identified to characterize possible biomarkers and therapeutic targets through co-analysis of downstream mRNAs and upstream lncRNAs. We depicted the mRNA transcriptome alteration in moderate and severe COVID-19 patients, and found evidences for heightened inflammation effect, hyperactivation of immune response and functional reduction of T cells in severe group. |