Accession | SAMC1398197 |
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Accession in Other Database | GSA-Human: HRS051082 |
Sample name | S_RNA01 |
Title | rRNA-depleted RNA isolated from peripheral blood |
Sample type | Human sample |
Organism | Homo sapiens |
Description | samples from severe patients |
Attributes | *Only part of the sample information is displayed on this page because the related dataset HRA000238 has not yet been registered in the Human Genetic Resource Management Platform of MOST. |
Release date | 2020-09-10 |
BioProject Accession | PRJCA003095 |
Submitter | Wenru Su (suwr3@mail.sysu.edu.cn) |
Organization | Zhongshan Ophthalmic Center,Sun Yat-sen University |
Submission date | 2023-06-18 |
Resource name | Description |
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GSA-Human (1) | - |
HRA000238 (Open Access) | We collected peripheral blood samples of 6 severe COVID-19 patients, 6 moderate COVID-19 patients and 4 healthy controls and performed multi-transcriptome sequencing of ncRNAs and mRNAs. Several miRNAs were identified to characterize possible biomarkers and therapeutic targets through co-analysis of downstream mRNAs and upstream lncRNAs. We depicted the mRNA transcriptome alteration in moderate and severe COVID-19 patients, and found evidences for heightened inflammation effect, hyperactivation of immune response and functional reduction of T cells in severe group. |