Accession | SAMC1565319 |
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Accession in Other Database | GSA-Human: HRS122670 |
Sample name | P3_Tumor_S5 |
Title | P3_Tumor_S5 |
Sample type | Human sample |
Organism | Homo sapiens |
Description | Profiling of human small bowel adenocarcinoma using single-cell RNA-seq |
Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA000483 in the GSA-Human system. |
Release date | 2022-11-28 |
BioProject Accession | PRJCA003992 |
Submitter | Jingwei Yang (tangfuchou@pku.edu.cn) |
Organization | Peking University |
Submission date | 2023-06-18 |
Resource name | Description |
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GSA-Human (1) | - |
HRA000483 (Controlled Access) | Small bowel adenocarcinoma is a type of rare malignant gastrointestinal tumors with a poor prognosis. To reveal molecular characteristics of malignant cells and microenvironment features of small bowel adenocarcinoma, we performed single-cell RNA-seq to analyze 48238 cells from tumor and adjacent normal tissues from 12 patients, which contain 6 duodenal cancer patients, 4 jejunal cancer patients and 2 ileal cancer patients. For 6 of these patients, we also adopted bulk whole exome sequencing to identity somatic mutations which may promote tumor progression and invasion. |